Detailed phenotyping reveals distinct trajectories of cardiovascular function and symptoms with exposure to modern breast cancer therapy
Background Breast cancer therapies are associated with a risk of cardiac dysfunction, most
commonly defined by changes in left ventricular ejection fraction (LVEF). Recently, the …
commonly defined by changes in left ventricular ejection fraction (LVEF). Recently, the …
Detailed echocardiographic phenotyping in breast cancer patients: associations with ejection fraction decline, recovery, and heart failure symptoms over 3 years of …
HK Narayan, B Finkelman, B French, T Plappert… - Circulation, 2017 - Am Heart Assoc
Background: Cardiovascular disease in patients with breast cancer is of growing concern.
The longitudinal effects of commonly used therapies, including doxorubicin and …
The longitudinal effects of commonly used therapies, including doxorubicin and …
Changes in cardiovascular biomarkers with breast cancer therapy and associations with cardiac dysfunction
B Demissei, RA Hubbard, L Zhang, AM Smith… - Journal of the American …, 2019 - jacc.org
Background There is a critical need to understand the role of biomarkers in the surveillance
of cardiac dysfunction in patients treated with cardiotoxic cancer therapy. We aimed to …
of cardiac dysfunction in patients treated with cardiotoxic cancer therapy. We aimed to …
Left ventricular ejection fraction and cardiac biomarkers for dynamic prediction of cardiotoxicity in early breast cancer
F Posch, T Niedrist, T Glantschnig, S Firla… - Frontiers in …, 2022 - frontiersin.org
Background/Purpose This study aims to quantify the utility of monitoring LVEF, hs-cTnT, and
NT-proBNP for dynamic cardiotoxicity risk assessment in women with HER2+ early breast …
NT-proBNP for dynamic cardiotoxicity risk assessment in women with HER2+ early breast …
[HTML][HTML] Cardiovascular function phenotypes in response to cardiotoxic breast cancer therapy
Cardiotoxicity, defined by declines in left ventricular ejection fraction (LVEF) and
symptomatic heart failure (HF), is a significant complication of commonly used treatments for …
symptomatic heart failure (HF), is a significant complication of commonly used treatments for …
Changes in cardiovascular biomarkers with breast cancer therapy and associations with cardiac dysfunction
BG Demissei, RA Hubbard, L Zhang… - Journal of the …, 2020 - Am Heart Assoc
Background We examined the longitudinal associations between changes in cardiovascular
biomarkers and cancer therapy–related cardiac dysfunction (CTRCD) in patients with breast …
biomarkers and cancer therapy–related cardiac dysfunction (CTRCD) in patients with breast …
Comprehensive assessment of changes in left ventricular diastolic function with contemporary breast cancer therapy
JN Upshaw, B Finkelman, RA Hubbard… - JACC: Cardiovascular …, 2020 - jacc.org
Objectives: This study determined the effects of doxorubicin and/or trastuzumab on diastolic
function and the relationship between diastolic function and systolic dysfunction …
function and the relationship between diastolic function and systolic dysfunction …
Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab
H Sawaya, IA Sebag, JC Plana, JL Januzzi… - Circulation …, 2012 - Am Heart Assoc
Background—Because cancer patients survive longer, the impact of cardiotoxicity
associated with the use of cancer treatments escalates. The present study investigates …
associated with the use of cancer treatments escalates. The present study investigates …
Nomogram for Predicting Risk of Cancer Therapy–Related Cardiac Dysfunction in Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
AF Yu, IH Lin, J Jorgensen… - Journal of the …, 2023 - Am Heart Assoc
Background Cancer therapy–related cardiac dysfunction (CTRCD) is an important treatment‐
limiting toxicity for patients with human epidermal growth factor receptor 2 (HER2)–positive …
limiting toxicity for patients with human epidermal growth factor receptor 2 (HER2)–positive …
Cardiac Dysfunction Among Breast Cancer Survivors: Role of Cardiotoxic Therapy and Cardiovascular Risk Factors
G Bostany, Y Chen, L Francisco, C Dai… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Cardiac dysfunction is the leading cause of mortality among 10-year breast
cancer survivors. Limited information regarding long-term risks of cardiac dysfunction after …
cancer survivors. Limited information regarding long-term risks of cardiac dysfunction after …
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