Accelerated plasminogen activator dose regimens for coronary thrombolysis

TC Wall, RM Califf, BS George, SG Ellis… - Journal of the American …, 1992 - Elsevier
To determine the clinical profile and efficacy of accelerated recombinant tissue-type
plasminogen activator (rt-PA) dose regimens, five different strategies of thrombolytic therapy …

Sixty-minute alteplase protocol: a new accelerated recombinant tissue-type plasminogen activator regimen for thrombolysis in acute myocardial infarction

DC Gulba, P Tanswell, R Dechend, M Sosada… - Journal of the American …, 1997 - jacc.org
Objectives. Our aim was to design and evaluate a new and easily administered recombinant
tissue-type plasminogen activator (rt-PA) regimen for thrombolysis in acute myocardial …

Acute coronary thrombolysis with recombinant human tissue-type plasminogen activator: initial patency and influence of maintained infusion on reocclusion rate

M Verstraete, AER Arnold, RW Brower, D Collen… - The American journal of …, 1987 - Elsevier
An intravenous infusion of 40 mg of recombinant tissue-type plasminogen activator (rt-PA)
was given intravenously over 90 minutes to 123 patients with acute myocardial infarction …

Improved thrombolysis with a modified dose regimen of recombinant tissue-type plasminogen activator

KL Neuhaus, W Feuerer, S Jeep-Tebbe… - Journal of the American …, 1989 - Elsevier
To improve further the patency rate of infarct-related coronary arteries, the following
accelerated dosage regimen of recombinant tissue-type plasminogen activator (rt-PA) was …

[HTML][HTML] Improved thrombolysis in acute myocardial infarction with front-loaded administration of alteplase: results of the rt-PA-APSAC patency study (TAPS)

KL Neuhaus, R Von Essen, U Tebbe, A Vogt… - Journal of the American …, 1992 - Elsevier
Thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) and anisoylated
plasminogen streptokinase activator (APSAC) in myocardial infarction has been proved to …

[HTML][HTML] Sequential combination thrombolytic therapy for acute myocardial infarction: results of the pro-urokinase and t-PA enhancement of thrombolysis (PATENT) …

SW Zarich, GJ Kowalchuk, WD Weaver… - Journal of the American …, 1995 - Elsevier
Objectives. The present study was designed to test the efficacy and safety of a sequential
combination of recombinant tissue-type plasminogen activator (rt-PA) and pro-urokinase in …

Randomized angiographic trial of recombinant tissue-type plasminogen activator (alteplase) in myocardial infarction

RJ Carney, GA Murphy, TR Brandt, PJ Daley… - Journal of the American …, 1992 - Elsevier
Clot dissolution with restoration of infarct-related artery blood flow is the likely mechanism for
the improved prognosis and mortality reduction seen after thrombolytic therapy of acute …

A new thrombolytic regimen for acute myocardial infarction using combination half dose tissue-type plasminogen activator with full dose streptokinase: a pilot study

CL Grines, SE Nissen, DC Booth, MC Branco… - Journal of the American …, 1989 - Elsevier
Because a previous study utilizing a combination of recombinant tissue-type plasminogen
activator (rt-PA) and urokinase demonstrated reduced reocclusion rates compared with rates …

Coronary thrombolysis with tissue-type plasminogen activator (t-PA): emerging strategies

BE Sobel - Journal of the American College of Cardiology, 1986 - Elsevier
Fundamental observations and the conceptual framework underlying coronary thrombolysis
have a history dating back to 1789. Recent enthusiasm for it is predicated on the recently …

Coronary angioplasty after recombinant tissue-type plasminogen activator in acute myocardial infarction: A report from the thrombolysis in myocardial infarction (TIMI) …

DO Williams, NA Ruocco, S Forman… - Journal of the American …, 1987 - Elsevier
To assess the utility of percutaneous transluminal coronary angioplasty after successful
thrombolytic therapy for patients with acute myocardial infarction, the outcome of 201 …