Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder
SS Girdler, PA Straneva, KC Light, CA Pedersen… - Biological …, 2001 - Elsevier
Background: This study was designed to examine basal and stress-induced levels of the
neuroactive progesterone metabolite, allopregnanolone, in women with premenstrual …
neuroactive progesterone metabolite, allopregnanolone, in women with premenstrual …
Progesterone metabolite allopregnanolone in women with premenstrual syndrome
AJ Rapkin, M Morgan, L Goldman, DW Brann… - Obstetrics & …, 1997 - Elsevier
OBJECTIVE: To evaluate the anxiolytic 3α-5α-reduced progesterone metabolite
allopregnanolone in the luteal phase of the menstrual cycle in women with premenstrual …
allopregnanolone in the luteal phase of the menstrual cycle in women with premenstrual …
Allopregnanolone levels and symptom improvement in severe premenstrual syndrome
EW Freeman, CA Frye, K Rickels… - Journal of clinical …, 2002 - journals.lww.com
Allopregnanolone is a neuroactive metabolite of progesterone and a barbiturate-like
modulator of central γ-aminobutyric acid A receptors that modify a range of behaviors …
modulator of central γ-aminobutyric acid A receptors that modify a range of behaviors …
Allopregnanolone concentrations and premenstrual syndrome
P Monteleone, S Luisi, A Tonetti… - European journal of …, 2000 - academic.oup.com
Objective To evaluate basal allopregnanolone and progesterone in both phases of the
menstrual cycle in women suffering from premenstrual syndrome (PMS) and their response …
menstrual cycle in women suffering from premenstrual syndrome (PMS) and their response …
Women with premenstrual dysphoric disorder have altered sensitivity to allopregnanolone over the menstrual cycle compared to controls—a pilot study
E Timby, T Bäckström, S Nyberg, H Stenlund… - …, 2016 - Springer
Rationale In premenstrual dysphoric disorder (PMDD), a condition that afflicts 3–8% of
women in fertile ages, the cyclic recurrence of debilitating mood symptoms is restricted to the …
women in fertile ages, the cyclic recurrence of debilitating mood symptoms is restricted to the …
[HTML][HTML] 5α-reductase inhibition prevents the luteal phase increase in plasma allopregnanolone levels and mitigates symptoms in women with premenstrual dysphoric …
PE Martinez, DR Rubinow, LK Nieman… - …, 2016 - nature.com
Abstract Changes in neurosteroid levels during the luteal phase of the menstrual cycle may
precipitate affective symptoms. To test this hypothesis, we stabilized neurosteroid levels by …
precipitate affective symptoms. To test this hypothesis, we stabilized neurosteroid levels by …
Allopregnanolone concentration and mood—a bimodal association in postmenopausal women treated with oral progesterone
L Andréen, I Sundström-Poromaa, M Bixo… - …, 2006 - Springer
Rationale Allopregnanolone effects on mood in postmenopausal women are unclear thus
far. Objectives Allopregnanolone is a neuroactive steroid with contradictory effects …
far. Objectives Allopregnanolone is a neuroactive steroid with contradictory effects …
Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators
L Andréen, S Nyberg, S Turkmen, G van Wingen… - …, 2009 - Elsevier
Certain women experience negative mood symptoms as a result of progesterone during the
luteal phase of the menstrual cycle, progestagens in hormonal contraceptives, or the …
luteal phase of the menstrual cycle, progestagens in hormonal contraceptives, or the …
Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone
L Andréen, I Sundström-Poromaa, M Bixo… - …, 2005 - Elsevier
Objective: To compare severity of negative mood and physical symptoms between women
with different progesterone, allopregnanolone, and pregnanolone plasma concentrations …
with different progesterone, allopregnanolone, and pregnanolone plasma concentrations …
[HTML][HTML] Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids …
L Hantsoo, CN Epperson - Neurobiology of Stress, 2020 - Elsevier
Premenstrual dysphoric disorder (PMDD) is a severe mood disorder with core symptoms
(affective lability, irritability, depressed mood, anxiety) and increased sensitivity to stress …
(affective lability, irritability, depressed mood, anxiety) and increased sensitivity to stress …