Objectives Our intention was to review all material published to date regarding
superantigens (SAgs) and allergy from an otorhinolaryngological viewpoint to understand …

Superantigens (SAgs) historically have been known for their lethal effects in toxic shock
syndrome and less devastating effects in food poisoning. More recently, a potential role for …

Staphylococcus aureus is the most common bacterium present in upper respiratory tract,
and the toxins it produced are involved in allergic inflammation pathogenesis. In this study …

OBJECTIVE: This review article has been prepared in order to enable the readers to
understand the role of staphylococcal superantigens (SsAgs) in atopic dermatitis (AD) …

To cite this article: Pastacaldi C, Lewis P, Howarth P. Staphylococci and staphylococcal
superantigens in asthma and rhinitis: a systematic review and meta‐analysis. Allergy 2011; …

Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …

Twenty-five percent of the population are permanent carriers of Staphylococcus aureus,
possibly producing a variety of toxins with superantigenic properties. Staphylococcal …

Background Staphylococcal exotoxins have been implicated in the pathogenesis of several
chronic inflammatory diseases including atopic dermatitis (AD), asthma, and, most recently …

Background Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with
colonization of the skin with Staphylococcus aureus known to produce toxins with …

Background The association between bacterial colonization and different forms of chronic
rhinosinusitis (CRS) has not been well documented. One of the most recent hypotheses is …