Aortic calcification and arterial stiffness burden in a chronic kidney disease cohort with high cardiovascular risk: baseline characteristics of the impact of phosphate …

NM Lioufas, E Pedagogos, CM Hawley… - American journal of …, 2020 - karger.com
Chronic kidney disease (CKD) is associated with excess cardiovascular morbidity and
mortality compared to the general population. Hyperphosphataemia, associated with …

Can we IMPROVE cardiovascular outcomes through phosphate lowering in CKD? Rationale and protocol for the IMpact of Phosphate Reduction On Vascular End …

N Lioufas, ND Toussaint, E Pedagogos, G Elder… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Patients with chronic kidney disease (CKD) are at heightened cardiovascular
risk, which has been associated with abnormalities of bone and mineral metabolism. A …

Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease

ME Seifert, L De Las Fuentes, M Rothstein… - American journal of …, 2013 - karger.com
Abstract Background/Aims: Cardiovascular disease (CVD) is increased in chronic kidney
disease (CKD), and contributed to by the CKD-mineral bone disorder (CKD-MBD). CKD …

A randomized trial on the effect of phosphate reduction on vascular end points in CKD (IMPROVE-CKD)

ND Toussaint, E Pedagogos, NM Lioufas… - Journal of the …, 2020 - journals.lww.com
Background Hyperphosphatemia is associated with increased fibroblast growth factor 23
(FGF23), arterial calcification, and cardiovascular mortality. Effects of phosphate-lowering …

[HTML][HTML] Reversal Of Arterial Disease by modulating Magnesium and Phosphate (ROADMAP-study): Rationale and design of a randomized controlled trial assessing …

EA Vermeulen, C Eelderink, T Hoekstra… - Trials, 2022 - Springer
Background Arterial stiffness and calcification propensity are associated with high
cardiovascular risk and increased mortality in chronic kidney disease (CKD). Both …

[HTML][HTML] A low fractional excretion of Phosphate/Fgf23 ratio is associated with severe abdominal Aortic calcification in stage 3 and 4 kidney disease patients

L Craver, A Dusso, M Martinez-Alonso, F Sarro… - BMC nephrology, 2013 - Springer
Background Vascular calcification (VC) contributes to high mortality rates in chronic kidney
disease (CKD). High serum phosphate and FGF23 levels and impaired phosphaturic …

Arterial stiffness as a risk factor for subclinical coronary artery calcification in predialysis chronic kidney disease: from the KNOW-CKD study

YY Hyun, H Kim, KH Oh, C Ahn, SK Park… - Kidney and Blood …, 2019 - karger.com
Abstract Background/Aims: Both arterial stiffness and coronary artery calcification (CAC) are
important predictors of cardiovascular disease in the general population and in chronic …

Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individuals

CM McEniery, BJ McDonnell, A So, S Aitken… - …, 2009 - Am Heart Assoc
Arterial stiffening is an independent predictor of mortality and underlies the development of
isolated systolic hypertension (ISH). A number of factors regulate stiffness, but arterial …

[HTML][HTML] Evaluating the effects of sevelamer carbonate on cardiovascular structure and function in chronic renal impairment in Birmingham: the CRIB-PHOS …

CD Chue, JN Townend, RP Steeds, CJ Ferro - Trials, 2011 - Springer
Background Serum phosphate is an independent predictor of cardiovascular morbidity and
mortality in patients with chronic kidney disease and the general population. There is …

[HTML][HTML] Progression of arterial stiffness is associated with changes in bone mineral markers in advanced CKD

R Krishnasamy, SJ Tan, CM Hawley, DW Johnson… - BMC nephrology, 2017 - Springer
Background Arterial stiffness is an independent predictor of all-cause and cardiovascular
mortality in patients with chronic kidney disease (CKD). There are limited prospective data …