Ferroptosis holds great potential in cancer treatment, but its efficacy is severely limited by a
low Fenton reaction efficacy. Meanwhile, the interactive relationship between Ferroptosis …

Ferroptosis has been considered as a promising pathway to overcome apoptosis-induced
tumor chemoresistance. However, the antitumor efficacy of ferroptosis-inducing agents is still …

Apoptosis-based treatment plays an important role in regulating the death of tumor cells (eg,
chemotherapy, radiotherapy, and immunotherapy). Nevertheless, cancer cells can escape …

Ferroptosis is a currently recognized non-apoptotic cell death mode based on reactive
oxygen species (ROS)-induced lipid peroxidation, which provides a promising strategy for …

As an approved chemotherapeutic drug for breast cancer (BC) therapy, the continuous
application of doxorubicin (DOX) is unfortunately limited by its poor selectivity and the …

Ferroptosis-based therapy exhibits promising prospects for the treatment of malignant
tumors. However, the practical therapeutic benefits of ferroptosis-based antitumor therapy …

Photodynamic therapy (PDT) induces apoptosis of cancer cells by generating cytotoxic
reactive oxygen species, the therapeutic effect of which, however, is impeded by …

Ferroptosis, an unusual non-apoptotic cell death caused by the iron-dependent
accumulation of lipid peroxide, enables the flexible design of an antitumor platform …

Ferroptosis is a newly found cell death mechanism, which could bypass apoptosis and
reverse multidrug resistance of tumors. However, efficient induction of tumor ferroptosis …

Ferroptosis is a recently discovered route of regulated cell death that offers the opportunities
for the treatment of chemotherapy-resistant tumor indications, but its efficacy can be affected …