[HTML][HTML] Phospholipase A2 receptor antibody IgG4 subclass improves sensitivity and specificity in the diagnosis of idiopathic membranous nephropathy

B Huang, Y Zhang, L Wang, W Xu, J Zhang… - Kidney and Blood …, 2019 - karger.com
Aims: The aim of this study was to develop a new method for detecting anti-phospholipase
A2 receptor-IgG4 to improve the sensitivity and specificity in the diagnosis of idiopathic …

[HTML][HTML] Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy

E Hoxha, U Kneißler, G Stege, G Zahner, I Thiele… - Kidney international, 2012 - Elsevier
The M-type phospholipase A2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy with detectable autoantibodies in the serum of up to 70% of …

M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy

LH Beck Jr, RGB Bonegio, G Lambeau… - … England Journal of …, 2009 - Mass Medical Soc
Background Idiopathic membranous nephropathy, a common form of the nephrotic
syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis …

Antiphospholipase A2 Receptor Autoantibodies: A Comparison of Three Different Immunoassays for the Diagnosis of Idiopathic Membranous Nephropathy

A Behnert, M Schiffer, J Müller-Deile… - Journal of …, 2014 - Wiley Online Library
Background. The recent identification of circulating autoantibodies directed towards the M‐
type phospholipase A2 receptor (PLA2R) has been a major advancement in the serological …

Antibodies to M-type phospholipase A2 receptor (PLA2R) in membranous lupus nephritis

E Garcia-Vives, C Solé, T Moliné, AM Alvarez-Rios… - Lupus, 2019 - journals.sagepub.com
Background Antibodies to M-type phospholipase A2 receptor (a-PLA2R) have been
identified in most patients with idiopathic membranous nephropathy, but the prevalence in …

Detection and monitoring PLA2R autoantibodies by LIPS in membranous nephropathy

PD Burbelo, LH Beck Jr, M Waldman - Journal of immunological methods, 2017 - Elsevier
Autoantibodies against the M-type phospholipase A 2 receptor (PLA 2 R) are specific
markers for primary membranous nephropathy (MN). Quantification of PLA 2 R …

Antiphospholipase A2 receptor autoantibodies: a step forward in the management of primary membranous nephropathy

B Obrisca, G Ismail, R Jurubita, C Baston… - BioMed research …, 2015 - Wiley Online Library
Since the identification of PLA2R (M‐type phospholipase A2 receptor) as the first human
antigenic target in primary membranous nephropathy (MN), perpetual progress has been …

Prevalence of serum anti M-type phospholipase A2 receptor antibody in primary membranous nephropathy: a single center experience

N Gopalakrishnan, P Abeesh… - Indian journal of …, 2016 - journals.lww.com
We conducted a prospective study to assess utility of detection of antibodies to
phospholipase A 2 receptor (PLA 2 R) in the serum of patients with membranous …

Anti‐PLA2R1 antibodies containing sera induce In vitro cytotoxicity mediated by complement activation

M Lateb, H Ouahmi, C Payré, V Brglez… - Journal of …, 2019 - Wiley Online Library
The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy (MN). However, the pathogenic role of anti‐PLA2R1 …

Diagnostic value of phospholipase A2 receptor in idiopathic membranous nephropathy: a systematic review and meta-analysis

SL Hu, D Wang, WJ Gou, QF Lei, TA Ma… - Journal of nephrology, 2014 - Springer
Background Detection of M-type phospholipase A 2 receptor (PLA 2 R) can be used in
serologic diagnosis of idiopathic membranous nephropathy (IMN), but there are limited data …