Contextual flexibility in Pseudomonas aeruginosa central carbon metabolism during growth in single carbon sources
Pseudomonas aeruginosa is an opportunistic human pathogen, particularly noted for
causing infections in the lungs of people with cystic fibrosis (CF). Previous studies have …
causing infections in the lungs of people with cystic fibrosis (CF). Previous studies have …
Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients
Pseudomonas aeruginosa is one of the major causes of morbidity and mortality of cystic
fibrosis patients. During the infection, the bacteria colonize the nutritional rich lung mucus …
fibrosis patients. During the infection, the bacteria colonize the nutritional rich lung mucus …
In Vivo Evidence of Pseudomonas aeruginosa Nutrient Acquisition and Pathogenesis in the Lungs of Cystic Fibrosis Patients
MS Son, WJ Matthews Jr, Y Kang… - Infection and …, 2007 - Am Soc Microbiol
One of the hallmarks of Pseudomonas aeruginosa infection in cystic fibrosis (CF) patients is
very-high-cell-density (HCD) replication in the lung, allowing this bacterium to induce …
very-high-cell-density (HCD) replication in the lung, allowing this bacterium to induce …
Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection
KM Jørgensen, T Wassermann… - …, 2015 - microbiologyresearch.org
Pseudomonas aeruginosa is the dominant pathogen infecting the airways of cystic fibrosis
(CF) patients. During the intermittent colonization phase, P. aeruginosa resembles …
(CF) patients. During the intermittent colonization phase, P. aeruginosa resembles …
Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections
V Behrends, B Ryall, JEA Zlosnik… - Environmental …, 2013 - Wiley Online Library
Pseudomonas aeruginosa forms chronic infections in the lungs of cystic fibrosis (CF)
patients, and is the leading cause of morbidity and mortality in patients with CF …
patients, and is the leading cause of morbidity and mortality in patients with CF …
High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs
Life-long bacterial infections in cystic fibrosis (CF) airways constitute an excellent model
both for persistent infections and for microbial adaptive evolution in complex dynamic …
both for persistent infections and for microbial adaptive evolution in complex dynamic …
Metabolic Network Analysis of Pseudomonas aeruginosa during Chronic Cystic Fibrosis Lung Infection
MA Oberhardt, JB Goldberg, M Hogardt… - Journal of …, 2010 - Am Soc Microbiol
System-level modeling is beginning to be used to decipher high throughput data in the
context of disease. In this study, we present an integration of expression microarray data …
context of disease. In this study, we present an integration of expression microarray data …
Nutritional Cues Control Pseudomonas aeruginosa Multicellular Behavior in Cystic Fibrosis Sputum
KL Palmer, LM Aye, M Whiteley - Journal of bacteriology, 2007 - Am Soc Microbiol
The sputum (mucus) layer of the cystic fibrosis (CF) lung is a complex substrate that provides
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …
Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung
A Kordes, M Preusse, SD Willger, P Braubach… - Nature …, 2019 - nature.com
Previous studies have demonstrated substantial genetic diversification of Pseudomonas
aeruginosa across sub-compartments in cystic fibrosis (CF) lungs. Here, we isolate P …
aeruginosa across sub-compartments in cystic fibrosis (CF) lungs. Here, we isolate P …
Cystic Fibrosis Sputum Supports Growth and Cues Key Aspects of Pseudomonas aeruginosa Physiology
KL Palmer, LM Mashburn, PK Singh… - Journal of …, 2005 - Am Soc Microbiol
The opportunistic human pathogen Pseudomonas aeruginosa causes persistent airway
infections in patients with cystic fibrosis (CF). To establish these chronic infections, P …
infections in patients with cystic fibrosis (CF). To establish these chronic infections, P …