[HTML][HTML] Indacaterol once-daily is equally effective dosed in the evening or morning in COPD

H Magnussen, C Verkindre, D Jack, D Jadayel… - Respiratory …, 2010 - Elsevier
Indacaterol is a novel, inhaled, long-acting β2-agonist providing 24-h bronchodilation with
once-daily (od) dosing in patients with COPD. In this double-blind, incomplete block …

Anticholinergic agents in asthma and COPD

NJ Gross - European journal of pharmacology, 2006 - Elsevier
Anticholinergic agents have important uses as bronchodilators for the treatment of
obstructive airway diseases, both asthma and, more particularly, chronic obstructive …

[图书][B] New drugs for asthma, allergy and COPD

TT Hansel, PJ Barnes - 2001 - books.google.com
This book provides a state-of-the-art account by academic respiratory physicians and senior
pharmaceutical industry personnel on the development of new drugs for asthma, allergy and …

[HTML][HTML] Single Inhaler LABA/LAMA for COPD

M Malerba, V Foci, F Patrucco, P Pochetti… - Frontiers in …, 2019 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common disabling disease
characterized by progressive airflow obstruction. Great efforts were spent in the …

A Holy Grail of asthma management: toward understanding how long‐acting β2‐adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids

MA Giembycz, M Kaur, R Leigh… - British journal of …, 2008 - Wiley Online Library
There is unequivocal evidence that the combination of an inhaled corticosteroid (ICS)—ie
glucocorticoid—and an inhaled long‐acting β2‐adrenoceptor agonist (LABA) is superior to …

The short, the long and the “ultra-long”: why duration of bronchodilator action matters in chronic obstructive pulmonary disease

KM Beeh, J Beier - Advances in therapy, 2010 - Springer
Bronchodilators are the cornerstone of symptomatic treatment for all chronic obstructive
pulmonary disease (COPD) severity stages when administered on a regular basis to prevent …

[HTML][HTML] Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD

M Cazzola, KM Beeh, D Price, N Roche - Pulmonary pharmacology & …, 2015 - Elsevier
The long-acting inhaled bronchodilators available for use in chronic obstructive pulmonary
disease (COPD) vary in their pharmacological class (β 2-adrenergic agonist or …

[HTML][HTML] Past, present and future—β2-adrenoceptor agonists in asthma management

MR Sears, J Lötvall - Respiratory medicine, 2005 - Elsevier
The β-adrenoceptor agonists (β-agonists) have been used to relieve bronchoconstriction for
at least 5000 years. β-agonists are based on adrenaline and early forms, such as …

Efficacy of a new once-daily long-acting inhaled β2-agonist indacaterol versus twice-daily formoterol in COPD

R Dahl, KF Chung, R Buhl, H Magnussen, V Nonikov… - Thorax, 2010 - thorax.bmj.com
Background Indacaterol is a long-acting inhaled β2-agonist (LABA) for the treatment of
chronic obstructive pulmonary disease (COPD). In previous studies, indacaterol provided 24 …

24-hour bronchodilator efficacy of single doses of indacaterol in patients with persistent asthma: comparison with placebo and formoterol

C LaForce, P Korenblat, P Osborne… - … medical research and …, 2009 - Taylor & Francis
Objective: To assess the 24-h bronchodilator efficacy and safety of single-dose indacaterol
in asthma. Methods: This was a five-period, double-blind, double-dummy, crossover study in …