The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Mitochondria produce adenosine triphosphate (ATP) while also generating high amounts of
reactive oxygen species (ROS) derived from oxygen metabolism. ROS are small but highly …

Object To explore the mechanisms of ovarian aging, we performed overall analysis on the
age-related alterations of gene expression profiles in mouse germinal vesicle (GV) stage …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients
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Many infertility specialists support the existence of a relationship between the levels of
mitochondrial DNA and the quality of the blastocysts. Despite the extensive use of pre …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

The decline of oocyte quality has profound impacts on fertilization, implantation, embryonic
development, and the genetic quality of future generations. One factor that is often ignored …

Mitochondria play a vital role in embryo development. They are the principal site of energy
production and have various other critical cellular functions. Despite the importance of this …

It is likely that there is an association between the fitness of mitochondria and their ability to
support normal cellular function. Oocytes are greatly enriched in the number of mitochondria …