Irreversible electroporation for the ablation of prostate cancer

A Karagiannis, J Varkarakis - Current Urology Reports, 2019 - Springer
Abstract Purpose of Review Although still considered experimental, focal irreversible
electroporation (IRE) as a primary treatment for prostate cancer (PCa) is considered one of …

Why we should not routinely apply irreversible electroporation as an alternative curative treatment modality for localized prostate cancer at this stage

JJ Wendler, R Ganzer, B Hadaschik, A Blana… - World journal of …, 2017 - Springer
Irreversible electroporation (IRE), a new tissue ablation procedure available since 2007,
could meet the requirements for ideal focal therapy of prostate cancer with its postulated …

[HTML][HTML] Irreversible electroporation for prostate cancer

S Ong, M Leonardo, T Chengodu, D Bagguley… - Life, 2021 - mdpi.com
Although it can be lethal in its advanced stage, prostate cancer can be effectively treated
when it is localised. Traditionally, radical prostatectomy (RP) or radiotherapy (RT) were used …

Focal irreversible electroporation for prostate cancer: functional outcomes and short-term oncological control

F Ting, M Tran, M Böhm, A Siriwardana… - Prostate cancer and …, 2016 - nature.com
Background: Current data on the use of irreversible electroporation (IRE) in the treatment of
prostate cancer (PCa) is limited. We aim to evaluate the safety, short-term functional and …

Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer

M Valerio, PD Stricker, HU Ahmed… - Prostate cancer and …, 2014 - nature.com
Background: To evaluate the safety and clinical feasibility of focal irreversible
electroporation (IRE) of the prostate. Methods: We assessed the toxicity profile and …

Median 5‐year outcomes of primary focal irreversible electroporation for localised prostate cancer

MJ Scheltema, B Geboers, A Blazevski… - BJU …, 2023 - Wiley Online Library
Objectives To evaluate longer‐term oncological and functional outcomes of focal irreversible
electroporation (IRE) as primary treatment for localised clinically significant prostate cancer …

[HTML][HTML] Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments

E Guenther, N Klein, S Zapf, S Weil, C Schlosser… - PloS one, 2019 - journals.plos.org
Background Irreversible Electroporation (IRE) is a novel image-guided tissue ablation
technology that induces cell death via very short but strong pulsed electric fields. IRE has …

Irreversible electroporation (IRE): a narrative review of the development of IRE from the laboratory to a prostate cancer treatment

A Blazevski, MJ Scheltema, A Amin… - BJU …, 2020 - Wiley Online Library
Introduction Whilst whole‐gland radical treatment is highly effective for prostate cancer
control, it has significant impact on quality of life and is unnecessary 'over‐treatment'in many …

[HTML][HTML] Irreversible Electroporation (IRE) for Prostate Cancer (PCa) Treatment: The State of the Art

E Faiella, D Santucci, D Vertulli, E Vergantino… - Journal of Personalized …, 2024 - mdpi.com
We evaluated the most recent research from 2000 to 2023 in order to deeply investigate the
applications of PCa IRE, first exploring its usage with primary intent and then salvage intent …

[HTML][HTML] Focal vs extended ablation in localized prostate cancer with irreversible electroporation; a multi-center randomized controlled trial

MJV Scheltema, W van den Bos, DM de Bruin… - BMC cancer, 2016 - Springer
Background Current surgical and ablative treatment options for prostate cancer (PCa) may
result in a high incidence of (temporary) incontinence, erectile dysfunction and/or bowel …