The perturbations in bile acids (BAs) in alcohol‐associated hepatitis (AH) and its
relationship to disease severity is not well defined. The aims of this study were to define (1) …

Bile acids (BAs) play important functions in the development of alcohol‐associated liver
disease (ALD). In the current study, urine BA concentrations in 38 patients with well …

Background Intestinal microbiota plays an important role in bile acid homeostasis. Aim To
study the structure of the intestinal microbiota and its function in bile acid homeostasis in …

Abstract Background Bile acids (BAs) are synthesized by the liver and modified by gut
bacteria, and may play an intermediary role between the gut microbiome and liver in …

Alcoholic liver disease and resultant cirrhosis are a major cause of morbidity and mortality
worldwide.(1) There is extensive literature documenting changes in the gut–liver axis as a …

Background Cirrhosis and alcohol can independently affect the gut–liver axis with systemic
inflammation. However, their concurrent impact in humans is unclear. Methods Our aim was …

Alcohol abuse with/without cirrhosis is associated with an impaired gut barrier and
inflammation. Gut microbiota can transform primary bile acids (BA) to secondary BAs, which …

ABSTRACT Severe Alcoholic Hepatitis (sAH) is an acute form of liver injury caused by
chronic and heavy alcohol drinking. A one-month corticosteroids course is the only sAH …

OBJECTIVES: The precipitous increase in nonalcoholic steatohepatitis (NASH) is
accompanied by a dramatic increase in the incidence of NASH-related hepatocellular …

Excessive alcohol consumption is a major global health problem. Individuals with alcoholic
liver disease often exhibit elevated serum total bile acids (TBAs). Nevertheless, the extent to …