Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene

GL Hammond, WP Bocchinfuso, M Orava, CL Smith… - Contraception, 1994 - Elsevier
A cross-over study of two oral contraceptive formulations, containing 30 μg ethinylestradiol
in combination with 150 μg desogestrel (Marvelon®) or 75 μg gestodene (Femovan®), has …

Prospective, open-label, noncomparative study to assess cycle control, safety and acceptability of a new oral contraceptive containing gestodene 60 μg and …

IC Barbosa, C Isaia Filho, D Faggion Jr, EC Baracat - Contraception, 2006 - Elsevier
OBJECTIVE: A prospective, open-label, noncomparative, multicenter study was carried out
in 163 women aged 18–39 (mean 25±5 years), who used an ultra-low-dose oral …

Pharmacokinetics and serum protein binding of gestodene and 3-keto-desogestrel in women after single oral administration of two different contraceptive formulations.

W Kuhnz, B Schütt, J Power, DJ Back - Arzneimittel-forschung, 1992 - europepmc.org
Two low-dose oral contraceptives, both containing the same dose of ethinyl estradiol (EE2,
CAS 57-63-6) but different progestins--gestodene (CAS 60282-87-3) and desogestrel (CAS …

Inhibition of ovulation by low-dose monophasic contraceptive containing gestodene

K Thomas, L Vankrieken - American journal of obstetrics and gynecology, 1990 - Elsevier
Ovulation inhibition by the monophasic oral contraceptive containing 75 μg of gestodene
and 30 wg of ethinyl estradiol was evaluated in 25 healthy volunteers for five cycles: a …

simultaneous determination of gestodene and ethinyl estradiol in contraceptive formulations by RP‐HPLC

A Laban, S Markovic, M Stankov, P Djurdjevic - Analytical letters, 2004 - Taylor & Francis
ABSTRACT A rapid and simple HPLC method for the determination of gestodene (GTD) and
ethinyl estradiol (ETE) in oral contraceptive formulations was developed and validated …

Comparative profiles of reliability, cycle control and side effects of two oral contraceptive formulations containing 150 μg desogestrel and either 30 μg or 20 μg ethinyl …

M ÅKerlund, A Rødez… - BJOG: An International …, 1993 - Wiley Online Library
Objective To compare two oral contraceptive pills, both containing 150 μg desogestrel, but
with either 20 μg (Mercilon®) or 30 μg (Marvelon®/Desolett®) ethinyl oestradiol (EE) …

Influence of gestodene and desogestrel as components of low-dose oral contraceptives on the pharmacokinetics of ethinyl estradiol (EE2), on serum CBG and on …

J Hammerstein, E Daume, A Simon, UH Winkler… - Contraception, 1993 - Elsevier
A randomized controlled clinical trial was undertaken over a 6-month treatment period with
two low-dose combined oral contraceptives (OC) to investigate whether the metabolism and …

Clinical experience with a modern low-dose oral contraceptive in almost 100,000 users

K Brill, T Norpoth, J Schnitker, M Albring - Contraception, 1991 - Elsevier
Efficacy, cycle control, tolerance, and adverse events were studied in a clinical Phase IV
study using a new progestogen, gestodene, in an amount of 75 μg combined with 30 μg …

Pharmacokinetics and pharmacodynamics of oral contraceptive steroids: factors influencing steroid metabolism

C Jung-Hoffmann, H Kuhl - American journal of obstetrics and gynecology, 1990 - Elsevier
The time-dependent alterations in the serum concentrations of ethinyl estradiol, gestodene,
and 3-keto-desogestrel during treatment with 30 µg of ethinyl estradiol+ 75 µg of gestodene …

Combined oral contraception with desogestrel/ethinyl estradiol: tolerability profile

AM Kaunitz - American journal of obstetrics and gynecology, 1993 - Elsevier
Since their introduction nearly 30 years ago, oral contraceptives have been widely
researched regarding their contraceptive and noncontraceptive effects. With proper usage …