For most organisms, iron is an essential nutrient that is both difficult to acquire from the
environment and toxic at high concentration. Therefore, to avoid deprivation or over …

Iron is one of the most important metals in the metabolism of many organisms, including
bacteria, in which it serves as a cofactor in multiple enzymatic reactions. Most of the earlier …

Iron is an essential element for nearly all living cells. Thus, the ability of bacteria to utilize
iron is a crucial survival mechanism independent of the ecological niche in which the …

For most living organisms, iron is both essential and potentially toxic, making the precise
maintenance of iron homeostasis necessary for survival. To manage this paradox, bacteria …

Obtaining and maintaining proper levels of iron are major challenges for most organisms
(reviews may be found in references 2, 9, and 10). The redox features that make iron such a …

Tight regulation of the expression of mRNAs encoding iron uptake proteins is essential to
control iron homeostasis and avoid intracellular iron toxicity. We show that many mRNAs …

Organisms generally respond to iron deficiency by increasing their capacity to take up iron
and by consuming intracellular iron stores. Escherichia coli, in which iron metabolism is …

Iron is an essential micronutrient, and, in the case of bacteria, its availability is commonly a
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …

The small RNA RyhB has recently been shown to negatively regulate a number of mRNAs
encoding dispensable iron‐using proteins in Escherichia coli. The resulting decrease in the …

All eukaryotes require iron although iron is not readily bioavailable. Organisms expend
much effort in acquiring iron and in response have evolved multiple mechanisms to acquire …