Cells with endothelial phenotype generated from adult peripheral blood have emerging
diagnostic and therapeutic potential. This study examined the lineage relationship between …

Dysfunctional and leaky blood vessels resulting from disruption of the endothelial cell (EC)
barrier accompanies numerous diseases. The EC barrier is established through endothelial …

Blood circulating endothelial cells (CECs) and circulating hematopoietic progenitor cells
(CPCs) represent two cell populations that are thought to play important roles in tissue …

The vascular system forms the largest surface in our body, serving as a critical interface
between blood circulation and our diverse organ/tissue environments. Thus, the vascular …

Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and
regeneration of blood vessels in perfusion-deficient tissues is a worthwhile therapeutic goal …

The endothelium is an expansive spatially distributed organ. 1 Endothelial cells participate
in a large number of physiological processes including the control of vasomotor tone, the …

Endothelial progenitor cells (EPCs) have been isolated postnatally from bone marrow,
blood, and both the intima and adventitia of conduit vessels. However, it is unknown whether …

The lung microvasculature is essential for gas exchange and commonly considered
homogeneous. We show that VEGFA from the epithelium is required for a distinct …

Background: Pulmonary arterial hypertension (PAH) is a life-threatening disorder of the
pulmonary circulation associated with loss and impaired regeneration of microvessels …

Despite considerable progress in the understanding of endothelial barrier regulation and the
identification of approaches that have the potential to improve endothelial barrier function …