ORF8/ORF8a: a difference between SARS-CoV-2 and SARS-CoV
M Zandi - European Respiratory Journal, 2022 - Eur Respiratory Soc
Recently in an editorial published as an “early view” paper in the European Respiratory
Journal, Hartsell et al.[1] reported that ORF8a has a role in SARS-CoV-2 infection. In figure …
Journal, Hartsell et al.[1] reported that ORF8a has a role in SARS-CoV-2 infection. In figure …
ORF9c and ORF10 as accessory proteins of SARS-CoV-2 in immune evasion
M Zandi - Nature Reviews Immunology, 2022 - nature.com
In a recent Perspective article in Nature Reviews Immunology (Wong, LY. R. & Perlman, S.
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related …
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related …
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression
The virus severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, is the causative
agent of the current COVID-19 pandemic. It possesses a large 30 kilobase (kb) genome that …
agent of the current COVID-19 pandemic. It possesses a large 30 kilobase (kb) genome that …
SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux
A Mozzi, M Oldani, ME Forcella, C Vantaggiato… - Iscience, 2023 - cell.com
Coronaviruses encode a variable number of accessory proteins that are involved in host-
virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 …
virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 …
SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70
H Jiang, H Zhang, Q Meng, J Xie, Y Li… - Cellular & molecular …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2. 1 As of July 16th, 2020, there were 13,579,581
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally …
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally …
[HTML][HTML] SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease
The orphan gene of SARS-CoV-2, ORF10, is the least studied gene in the virus responsible
for the COVID-19 pandemic. Recent experimentation indicated ORF10 expression …
for the COVID-19 pandemic. Recent experimentation indicated ORF10 expression …
Metabolic and mitochondria alterations induced by SARS‐CoV‐2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10
BD López‐Ayllón, S Marin… - Journal of Medical …, 2024 - Wiley Online Library
Antiviral signaling, immune response and cell metabolism are dysregulated by SARS‐CoV‐
2, the causative agent of COVID‐19. Here, we show that SARS‐CoV‐2 accessory proteins …
2, the causative agent of COVID‐19. Here, we show that SARS‐CoV‐2 accessory proteins …
[HTML][HTML] Repeated Loss of ORF8 Expression in Circulating SARS-CoV-2 Lineages
R Hisner, D Gueli, TP Peacock - image, 2023 - virological.org
SARS-CoV-2, like other coronaviruses, expresses a variety of non-structural, structural and
accessory proteins. Accessory proteins in coronaviruses are defined as proteins that are not …
accessory proteins. Accessory proteins in coronaviruses are defined as proteins that are not …
SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths, posing a substantial threat to global public health. Viruses evolve different strategies …
deaths, posing a substantial threat to global public health. Viruses evolve different strategies …
The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis
S Lenhard, S Gerlich, A Khan, S Rödl… - Journal of Cell …, 2023 - rupress.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses high
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …