Publisher Summary This chapter examines opportunities afforded by the publication of the
fly genome, and focuses on more specific information concerning Drosophila. The chapter …

This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila
due to rapid developments in molecular genetics approaches that overcome the difficulties …

Neuropeptides in insects act as neuromodulators in the central and peripheral nervous
system and as regulatory hormones released into the circulation. The functional roles of …

D rosophila melanogaster is since decades the most important invertebrate model. With the
publishing of the genome sequence, Drosophila also became a pioneer in (neuro) peptide …

Neuropeptides regulate most, if not all, biological processes in the animal kingdom, but only
seven have been isolated and sequenced from Drosophila melanogaster. In analogy with …

Neuropeptides form the most diverse class of chemical messenger molecules in metazoan
nervous systems. They are usually generated from biosynthetic precursor polypeptides by …

The twelve sequenced Drosophila genomes show the vast majority of neurohormone and
neuropeptide genes to be very well conserved. Nonetheless, the gene encoding the …

Recent genetic analyses in worms, flies, and mammals illustrate the importance of bioactive
peptides in controlling numerous complex behaviors, such as feeding and circadian …

Background Neuropeptides comprise the most diverse group of neuronal signaling
molecules. They often occur as multiple sequence-related copies within single precursors …