Recently, we have reported a series of isatin hydrazone, two of them, namely, 3-((2, 6-
dichlorobenzylidene) hydrazono) indolin-2-one (1) and 3-((2-chloro-6-fluorobenzylidene) …

Isatin derivatives potentially act on various biological targets. In this article, a series of novel
isatin-hydrazones were synthesized in excellent yields. Their cytotoxicity was tested against …

In this study, we investigated the in vitro antiproliferative activities and performed
computational studies of newly synthesized fluorinated isatin-hydrazones. The chemical …

The docking studies on CDK2 and GSK-3β inspired us to synthesis a series of indoline-2, 3-
dione hydrazones 10a–l. Treatment of indoline-2, 3-dione derivatives 7a–d with hydrazine …

A set of novel Schiff bases of isatin were synthesized and characterized by reaction of isatin
with various aromatic or heterocyclic primary amines. Cytotoxic activities for some of the …

Merging isatin and arylhydrazone moieties constitutes an efficient strategy to access new
potential anticancer derivatives. Consequently, 14 hydrazone‐isatin derivatives were …

Human health in the current medical era is facing numerous challenges, especially cancer.
So, the therapeutic arsenal for cancer should be unremittingly enriched with novel small …

Keeping in view the pharmacological properties of indolinones as promising scaffold as
kinase inhibitors, herein, a novel series of 3-hydrazonoindolin-2-one derivatives bearing 3 …

Iridoids commonly found in plants as secondary metabolites have been reported to possess
significant biological activities such as anticancer, antioxidant, hypoglycemic, antimicrobial …

Tyrosine protein kinases (TKs) have been proved to play substantial roles on many cellular
processes and their overexpression tend to be found in various types of cancers. Therefore …