Statins for the primary prevention of cardiovascular disease in the elderly

RN Lowe, JP Vande Griend… - The Consultant …, 2015 - ingentaconnect.com
Objective: The objective is to review the evidence evaluating the efficacy of statin therapy for
primary prevention of cardiovascular (CV) disease in the elderly. Data Sources: A literature …

Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence

R Ali, KP Alexander - The American Journal of Geriatric Pharmacotherapy, 2007 - Elsevier
BACKGROUND:: Although statins have been demonstrated to be beneficial for secondary
prevention in the elderly, their use for primary prevention has not been well described …

Statins in primary prevention in people over 80 years

E Marcellaud, J Jost, A Tchalla, J Magne… - The American Journal of …, 2023 - Elsevier
In the much older population (≥ 80 years), the management of cardiovascular diseases
requires specific research to avoid a plain transposition of medical practice from younger …

Statins for the primary prevention of cardiovascular events in elderly patients: a picture from clinical practice without strong evidence from clinical trials

G Trifirò, M Alacqua, S Corrao, M Tari… - Journal of the American …, 2008 - iris.univr.it
Statins have been demonstrated to be beneficial for secondary prevention of cardiovascular
(CV) events also in the elderly. However, a great debate is ongoing about the actual …

Benefits and risks for primary prevention with statins in the elderly

JP Joseph, M Afonso, D Berdai, N Salles… - … (Paris, France: 1983), 2015 - europepmc.org
Method Methodic review of large randomized clinical trials and meta-analyzes that included
patients 75 years and older treated with statins in primary prevention. Results Since the …

Unanswered Questions: The Use of Statins in Older People to Prevent Cardiovascular Event Effects of Statins on Risk of Coronary Disease: A Meta-Analysis of …

LM Birch - Journal of the American Geriatrics Society, 2002 - search.ebscohost.com
Focuses on the use of statins in older people to prevent cardiovascular event. Estimation of
the risk reduction of coronary heart disease (CHD) and total mortality associated with statin …

Statins for primary prevention of cardiovascular disease in elderly patients: systematic review and meta-analysis

M Teng, L Lin, YJ Zhao, AL Khoo, BR Davis, QW Yong… - Drugs & aging, 2015 - Springer
Background Statins have been shown to be beneficial in primary and secondary prevention
settings; however, their role in the elderly remains a clinical conundrum, given that age …

Statins for primary prevention in the elderly: the importance of rigorous evidence

SJ Nicholls, AJ Nelson - JAMA, 2020 - jamanetwork.com
An aging population brings considerable challenges for health care systems. The increase
in disease burden and economic investment required for the care of older patients is in …

Real-life benefits of statins for cardiovascular prevention in elderly subjects: a population-based cohort study

J Bezin, N Moore, Y Mansiaux, PG Steg… - The American Journal of …, 2019 - Elsevier
Objectives The benefits of initiating statins in the elderly remains debated. We evaluated the
effects of initiating statins in the elderly, according to cardiovascular risk. Methods This …

Initiation of statin therapy: are there age limits?

DA Desai, S Zakaria, P Ouyang - Current atherosclerosis reports, 2012 - Springer
Cardiovascular disease (CVD) is the leading cause of death, with a higher prevalence in
older adults who form an increasing proportion of the population of the United States. Statin …