Mitochondrial degeneration is considered to play an important role in the development of
diabetic peripheral neuropathy in humans. Mitochondrial degeneration and the …

Peripheral neuropathy is a common and debilitating complication of diabetes and
prediabetes. Recent clinical studies have identified an association between the …

Mitochondrial-mediated oxidative stress in response to high glucose is proposed as a
primary cause of dorsal root ganglia (DRG) neuron injury in the pathogenesis of diabetic …

Diabetic peripheral neuropathy (DPN) is a common complication affecting more than one
third of diabetes mellitus (DM) patients. Although all cellular components participating in …

Peripheral neuropathy (PN) is the most common complication of prediabetes and diabetes.
PN causes severe morbidity for Type 2 diabetes (T2D) and prediabetes patients, including …

Diabetic neuropathy is a major complication of diabetes that involves the sensory and
autonomic nervous systems and leads to significant morbidity and impact on quality of life of …

Adenosine monophosphate-activated protein kinase (AMPK) has been studied for its myriad
metabolic and mitochondrial benefits in several chronic diseases. Recent studies have …

The Diabetes Control and Complications Trial (DCCT) established the importance of
hyperglyemia and other consequences of insulin deficiency in the pathogenesis of diabetic …

Diabetic neuropathy is a major complication of diabetes that affects the sensory and
autonomic nervous systems and leads to significant morbidity and impact on the quality of …

OBJECTIVE Impairments in mitochondrial physiology may play a role in diabetic sensory
neuropathy. We tested the hypothesis that mitochondrial dysfunction in sensory neurons is …