This study was carried out to test the hypothesis that purine nucleotide‐generating pathways
are required for ligand‐stimulated oocyte maturation in meiotically arrested cumulus cell …

To test the hypothesis that culture conditions influence meiotic regulation in mouse oocytes,
we have examined the effects of six culture media, four organic buffers, and pH on …

We have examined adenosine (Ado) suppression of FSH‐induced germinal vesicle
breakdown (GVB) and its relationship to purine de novo synthesis. Oocyte‐cumulus cell …

The selection of culture media and supplements therein has a tremendous impact on the
regulation of oocyte maturation in vitro. In the present study, we have evaluated how altering …

The presented data demonstrate a dose‐dependent inhibition of spontaneous meiosis of
cumulus‐enclosed rat oocytes by guanosine, hypoxanthine, and adenosine. The inhibition …

Previous studies have suggested a critical role for purines in the maintenance of mouse
oocytes in meiotic arrest. If so, then disrupting specific purine metabolic pathways in vivo …

In this study, the effect of different energy sources used in Eagle's minimum essential
medium on the meiotic maturation of mouse oocytes in culture was examined. The effects of …

The efficacy of follicle‐stimulating hormone (FSH), epidermal growth factor (EGF), and
dibutyryl cGMP (dbcGMP) as inducers of germinal vesicle breakdown (GVBD) in cumulus …

Oocyte cumulus complexes (OCC) were isolated from antral follicles of proestrous hamsters
prior to the luteinizing hormone (LH)/follicle-stimulating hormone (FSH) surge and then …

In this study we tested the hypothesis that the pentose phosphate pathway (PPP)
participates in the meiotic induction of mouse oocytes. The electron acceptors methylene …