The effects of glucose and cumulus cells on oocyte ATP levels and germinal vesicle
breakdown (GVB) in isolated mouse oocytes have been examined. Oocyte-cumulus cell …

The effects of follicle-stimulating hormone (FSH) and cyclic guanosine 3′, 5′-
monophosphate (cGMP) on spontaneous oocyte maturation and cyclic adenosine 3′, 5 …

It has been known for more than fifty years that oocytes present in preovulatory antral
follicles do not resume meiosis, whereas these oocytes do resume meiosis if liberated from …

To analyze the potential mechanisms by which hypoxanthine and adenosine maintain
meiotic arrest in mouse oocytes this study focused on:(1) the uptake and metabolism of …

This study was performed to address the possible role of pyruvate in meiotic induction in
mouse oocytes. Cumulus cell-enclosed oocytes from primed, immature mice were cultured …

This study was carried out to evaluate the possible role of adenosine uptake and
metabolism in mediating the inhibitory actions of this nucleoside on spontaneous mouse …

Summary ― In vitro maturation of rabbit cumulus-enclosed oocytes was fully inhibited
in a-amanitin-(100 8g/ml) and cycloheximide-(5 pg/ml) supplemented media. The inhibition …

Experiments were carried out to determine the effect of different macromolecules on the
follicle‐stimulating hormone (FSH)‐induced maturation of mouse oocytes in culture …

Guanyl nucleotide binding‐proteins, or G‐proteins, are ubiquitous molecules that are
involved in cellular signal transduction mechanisms. Because a role has been established …

We have developed an assay that can detect relative changes in the amount of a non-cAMP
inhibitor of maturation present in cumulus cells (Eppig et al., 1983, Dev. Biol., 100: 39-49) …