Genetic susceptibility to tuberculosis

S Malik, E Schurr - 2002 - degruyter.com
Tuberculosis, caused by the human pathogen Mycobacterium tuberculosis (M. tuberculosis),
affects an estimated 8 million people annually, resulting in approximately 2 million deaths …

Ethnic-specific genetic associations with pulmonary tuberculosis

JC Delgado, A Baena, S Thim… - The Journal of infectious …, 2002 - academic.oup.com
Several susceptibility-associated genetic polymorphisms have been proposed to explain
differential susceptibility to tuberculosis (TB) disease progression in different populations …

The genetics of susceptibility to tuberculosis: progress and challenges

AA Rudko, EY Bragina, VP Puzyrev… - Asian Pacific Journal of …, 2016 - Elsevier
Tuberculosis is a global pressing healthcare issue in the modern world. Host genetics is an
important modifier of the disease risk. Genetic and genomic studies aim to reveal key …

Host genetic susceptibility to human tuberculosis

RJ Bellamy, AVS Hill - Genetics and Tuberculosis: Novartis …, 1998 - Wiley Online Library
Convincing evidence exists that host genes influence the outcome of infection in human
tuberculosis. We are employing two complementary strategies to find the genes involved, a …

[引用][C] Genetic susceptibility to tuberculosis

MJ Newport, JM Blackwell - BAILLIERES …, 1997 - … TINDALL 24-28 OVAL RD, LONDON …

Identifying genetic susceptibility factors for tuberculosis in Africans: a combined approach using a candidate gene study and a genome-wide screen.

R Bellamy - Clinical Science (London, England: 1979), 2000 - europepmc.org
There is convincing evidence that host genes affect the outcome of infection in human
tuberculosis. Two complementary strategies were used to identify the genes involved. A …

Co‐evolution of Mycobacterium tuberculosis and Homo sapiens

D Brites, S Gagneux - Immunological reviews, 2015 - Wiley Online Library
The causative agent of human tuberculosis (TB), M ycobacterium tuberculosis, is an obligate
pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11. 2

T Thye, FO Vannberg, SH Wong, E Owusu-Dabo… - Nature …, 2010 - nature.com
We combined two tuberculosis genome-wide association studies from Ghana and The
Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located …

Epidemiología molecular de la tuberculosis

P Coll, DG de Viedma - Enfermedades Infecciosas y Microbiología Clínica, 2018 - Elsevier
The application of genotyping tools allowed us to discriminate between the Mycobacterium
tuberculosis isolates obtained in the laboratory. The differentiation between single strains …

[HTML][HTML] Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles

NTT Thuong, SJ Dunstan, TTH Chau… - PLoS …, 2008 - journals.plos.org
Although host genetics influences susceptibility to tuberculosis (TB), few genes determining
disease outcome have been identified. We hypothesized that macrophages from individuals …