Tissue-specific expression of apolipoprotein AI (ApoA-I) is regulated by the 5′-flanking region of the human ApoA-I gene.
K Higuchi, SW Law, JM Hoeg, UK Schumacher… - Journal of Biological …, 1988 - ASBMB
We have isolated and characterized a 2.5-kilobase pairs genomic DNA fragment which
includes the 5′-flanking region and the first and second exons of the human apolipoprotein …
includes the 5′-flanking region and the first and second exons of the human apolipoprotein …
[HTML][HTML] Transcriptional regulation of the apolipoprotein AI gene. Species-specific expression correlates with rates of gene transcription.
M Sorci-Thomas, MW Kearns - Journal of Biological Chemistry, 1991 - Elsevier
Previous studies have shown that the abundance of apoA-I mRNA in liver and intestine
correlates with a 2-3-fold species-specific difference in the plasma concentration of high …
correlates with a 2-3-fold species-specific difference in the plasma concentration of high …
[HTML][HTML] Structure and expression of the human apolipoprotein A-IV gene.
NA Elshourbagy, DW Walker, YK Paik… - Journal of Biological …, 1987 - Elsevier
We have isolated the human apolipoprotein (apo) A-IV gene from a cosmid library and
determined its complete nucleotide sequence. The gene contains three exons of 162, 127 …
determined its complete nucleotide sequence. The gene contains three exons of 162, 127 …
Evolutionary distinct mechanisms regulate apolipoprotein AI gene expression: differences between avian and mammalian apoA-I gene transcription control regions.
S Lamon-Fava, R Sastry, S Ferrari… - Journal of lipid …, 1992 - Elsevier
In mammals, the apolipoprotein (apo) AI gene is expressed predominantly in liver and
intestine, while in avian species it is expressed in all tissues. Although liver and intestine are …
intestine, while in avian species it is expressed in all tissues. Although liver and intestine are …
[HTML][HTML] A polymorphism (G–> A transition) in the-78 position of the apolipoprotein AI promoter increases transcription efficiency
E Angotti, E Mele, F Costanzo… - Journal of Biological …, 1994 - Elsevier
AG–> A transition at-78 base pairs from the transcription start site of the apolipoprotein AI
(apoA-I) gene has been associated with increased apoA-I serum levels in humans. We …
(apoA-I) gene has been associated with increased apoA-I serum levels in humans. We …
[HTML][HTML] Expression and characterization of human apolipoprotein AI in Chinese hamster ovary cells.
JB Mallory, PJ Kushner, AA Protter, CL Cofer… - Journal of Biological …, 1987 - Elsevier
We produced human apolipoprotein AI (apoA-I) in Chinese hamster ovary (CHO) cells. The
CHO cells were transfected with an expression plasmid which placed the human apoA-I …
CHO cells were transfected with an expression plasmid which placed the human apoA-I …
Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells
RL Widom, JAA Ladias, S Kouidou… - Molecular and cellular …, 1991 - Taylor & Francis
The gene coding for apolipoprotein AI (apoAI), a plasma protein involved in the transport of
cholesterol and other lipids in the plasma, is expressed predominantly in liver and intestine …
cholesterol and other lipids in the plasma, is expressed predominantly in liver and intestine …
Isolation and characterization of the human apolipoprotein AI gene.
SK Karathanasis, VI Zannis… - Proceedings of the …, 1983 - National Acad Sciences
We have recently shown that an inherited polymorphism occurring in the human
apolipoprotein AI (apo AI) gene is related to decreased high density lipoprotein and apo AI …
apolipoprotein AI (apo AI) gene is related to decreased high density lipoprotein and apo AI …
Factors participating in the liver-specific expression of the human apolipoprotein A-II gene and their significance for transcription
P Cardot, J Chambaz, D Kardassis, C Cladaras… - Biochemistry, 1993 - ACS Publications
A-II (apoA-II) gene in cell cultures is controlled by a complex set of regulatory elements AN
[Chambaz, et al.(1991) J. Biol. Chem. 266, 11676-11685; Cardot, et al.(1991) J. Biol. Chem …
[Chambaz, et al.(1991) J. Biol. Chem. 266, 11676-11685; Cardot, et al.(1991) J. Biol. Chem …
G to A substitution in the promoter region of the apolipoprotein AI gene is associated with elevated serum apolipoprotein AI and high density lipoprotein cholesterol …
M Jeenah, A Kessling, N Miller… - Molecular biology & …, 1990 - europepmc.org
We have determined the sequence of 250 bases 5'of the transcriptional start site of the
apolipoprotein AI gene in a human individual with high serum concentrations of apo AI. One …
apolipoprotein AI gene in a human individual with high serum concentrations of apo AI. One …