Objective: To compare a low-dose (1 μg) corticotropin stimulation test with the more
standard (250 μg) test for the diagnosis of relative adrenal insufficiency. Design: Diagnostic …

Objective To determine whether a baseline (random) cortisol concentration< 25 μg/dL in
patients with septic shock was a better discriminator of adrenal insufficiency than the …

Objective: To evaluate the concept of relative adrenal insufficiency necessitating
corticosteroid therapy in septic shock. Design: Retrospective study. Setting: Medical-surgical …

Objective To investigate, in patients with severe septic shock, the adrenocortical function
assessed by daily plasma cortisol determinations during the first 72 h and by the short …

Rationale: Diagnosis of adrenal insufficiency in critically ill patients has relied on random or
cosyntropin-stimulated cortisol levels, and has not been corroborated by a more accurate …

Objective: To refine the value of baseline and adrenocorticotropin hormone (ACTH)-
stimulated cortisol levels in relation to mortality from severe sepsis or septic shock. Design …

It is unclear whether a random plasma cortisol measurement and the corticotropin (ACTH)
test adequately reflect glucocorticoid secretory capacity in critical illness. This study aimed to …

Objective: To examine recent literature regarding corticotherapy in critically ill patients
suffering from sepsis, acute respiratory distress syndrome (ARDS), and severe community …

Adequate adrenocortical function is essential to survive critical illness. Most critically ill
patients display an elevated plasma cortisol level, reflecting activation of the pituitary …

Objective: The definition of normal adrenal function in critically ill patients remains
controversial, despite a large body of literature. We review the clinical presentation …