[HTML][HTML] Emerging systemic treatments for atopic dermatitis

SM Ferrucci, S Tavecchio, AV Marzano… - Dermatology and …, 2023 - Springer
Atopic dermatitis (AD) is a chronic or chronically relapsing inflammatory skin disease which
results from a complex, multifaceted interaction between environmental factors in genetically …

New and emerging biologics for atopic dermatitis

W Baghoomian, CH Na, EL Simpson - American Journal of Clinical …, 2020 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by
complex pathophysiology involving both skin barrier dysfunction and aberrant type 2 …

Targeting cytokines and signaling molecules related to immune pathways in atopic dermatitis: therapeutic implications and challenges

HO Kim - Archives of Pharmacal Research, 2022 - Springer
Although atopic dermatitis (AD) is primarily a Th2-driven disease, it shows high
heterogeneity with additional variable contributions of the Th22, Th17, and Th1 pathways …

Drug evaluation review: dupilumab in atopic dermatitis

JD Hamilton, B Ungar, E Guttman-Yassky - Immunotherapy, 2015 - Taylor & Francis
Atopic dermatitis (AD) is characterized by type 2 helper T (Th2) cell-driven inflammation.
Dupilumab is a fully human monoclonal antibody directed against the IL-4 receptor α subunit …

Atopic dermatitis treatment: Current state of the art and emerging therapies.

JI Silverberg - Allergy & Asthma Proceedings, 2017 - search.ebscohost.com
Background: Atopic dermatitis (AD) can be debilitating and often requires the use of
combination topical and systemic therapy to achieve adequate disease control. Methods: A …

Spotlight on dupilumab in the treatment of atopic dermatitis: design, development, and potential place in therapy

AM D'Erme, M Romanelli… - Drug Design, Development …, 2017 - Taylor & Francis
Atopic dermatitis (AD) is among the most common inflammatory skin diseases in children
and adults in industrialized countries. Up to one-third of adults (probably a smaller …

[PDF][PDF] Advances in management of atopic dermatitis: new therapies and novel uses of existing treatments

EP Chase, AW Armstrong - Seminars in Cutaneous Medicine and …, 2012 - cdn.mdedge.com
Atopic dermatitis (AD) is a chronic inflammatory skin condition marked by intensely pruritic,
eczematous changes. First-line therapy includes topical corticosteroids during an …

Efficacy of biologics in atopic dermatitis

J Wu, E Guttman-Yassky - Expert Opinion on Biological Therapy, 2020 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a heterogeneous disease. Recent advancements in
understanding AD pathogenesis resulted in the exponential expansion of its therapeutic …

Biologic therapy for atopic dermatitis: moving beyond the practice parameter and guidelines

M Boguniewicz - The Journal of Allergy and Clinical Immunology: In …, 2017 - Elsevier
Atopic dermatitis (AD), a common chronic pruritic inflammatory skin disease, impacts the
quality of life of patients and caregivers and has become a global health problem. It is …

Dupilumab for Moderate-to-Severe Atopic Dermatitis.

R Vangipuram, SK Tyring - Skin Therapy Letter, 2017 - europepmc.org
Atopic dermatitis (AD) is the most common chronic inflammatory disease affecting 2-10% of
adults and up to 15-30% of children. Despite a rising prevalence, effective and safe …