Furthering Deceased Donor Intervention Research in Canada and the United Kingdom

HI Opdam - Transplantation, 2024 - journals.lww.com
Research is important to improve the quality and availability of transplantable organs.
Deceased donor research has been hindered by ethical and practical challenges. This …

Are transplant recipients human subjects when research is conducted on organ donors?

KG Heffernan, AK Glazier - Hastings Center Report, 2017 - Wiley Online Library
Interventional research on deceased organ donors and donor organs prior to transplant
holds the promise of reducing the number of patients who die waiting for an organ by …

Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors

F D'Aragon, S Dhanani, F Lamontagne, DJ Cook… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Research on the management of deceased organ donors aims to improve the
number and quality of transplants and recipient outcomes. In Canada, this research is …

[HTML][HTML] Deceased donor intervention research: A survey of transplant surgeons, organ procurement professionals, and institutional review board members

JR Rodrigue, S Feng, AC Johansson, AK Glazier… - American Journal of …, 2016 - Elsevier
Innovative deceased donor intervention strategies have the potential to increase the number
and quality of transplantable organs. Yet there is confusion over regulatory and legal …

Clinicians' Attitudes and Perspectives on Ante-Mortem Interventions in Deceased Organ Donation: An International Interview Study

S Shahrestani, WJ Hawthorne, HC Pleass… - …, 2018 - journals.lww.com
Materials and Methods Thirty clinicians (ICU physicians, donor coordinators, transplant
physicians, transplant surgeons and policy makers) from eight countries (Australia, New …

[HTML][HTML] Research and innovation in organ donation: recommendations from an international consensus forum

M Escoto, F Issa, F Cayouette, H Consolo… - Transplantation …, 2023 - journals.lww.com
Background. This report provides recommendations from the Research and Innovation
domain as part of the International Donation and Transplantation Legislative and Policy …

[HTML][HTML] Research and innovation in the deceased donor

DA Gerber, A Glazier, S Feng - American Journal of Transplantation, 2014 - Elsevier
The authors use a recently completed multidonor hospital study that involved treating donors
with albuterol prior to organ recovery as an example of a recent low-risk trial to demonstrate …

Organ donation and transplantation: the view from Canada

GA Knoll, KJ Tinckam - Transplantation, 2015 - journals.lww.com
Canada is the second-largest country in the world with its relatively small population
(approximately 35 million) divided into 10 provinces and 3 territories. Administration and …

Developing Guidance for Donor Intervention Randomized Controlled Trials: Initial Discussions From the Canada-United Kingdom 2022 Workshop

M Slessarev, KL Bain, J Basmaji… - …, 2024 - journals.lww.com
Background. Donor interventions, including medications, protocols, and medical devices
administered to donors, can enhance transplantable organ quality and quantity and …

The impact of therapeutic hypothermia used to treat anoxic brain injury after cardiopulmonary resuscitation on organ donation outcomes

C Wright, MS Patel, X Gao, M Witt, M Sally… - Therapeutic …, 2019 - liebertpub.com
Therapeutic hypothermia (TH) is clinically used to improve neurologic outcomes in patients
with anoxic brain injury after cardiopulmonary resuscitation (CPR). For patients that regress …