The role of miR-497-5p in myofibroblast differentiation of LR-MSCs and pulmonary fibrogenesis

X Chen, C Shi, C Wang, W Liu, Y Chu, Z Xiang, K Hu… - Scientific reports, 2017 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal fibrotic lung disease
characterized by profound changes in stem cell differentiation, epithelial cell phenotypes …

miR-877-3p targets Smad7 and is associated with myofibroblast differentiation and bleomycin-induced lung fibrosis

C Wang, S Gu, H Cao, Z Li, Z Xiang, K Hu, X Han - Scientific reports, 2016 - nature.com
Myofibroblast differentiation of lung resident mesenchymal stem cells (LR-MSC) plays an
important role in idiopathic pulmonary fibrosis. By comparing the expression profiles of …

MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis

S Das, M Kumar, V Negi, B Pattnaik… - American journal of …, 2014 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a fatal disorder resulting from the progressive
remodeling of lungs, with no known effective treatment. Although transforming growth factor …

[HTML][HTML] MiR-338* targeting smoothened to inhibit pulmonary fibrosis by epithelial-mesenchymal transition

Y Zhuang, J Dai, Y Wang, H Zhang, X Li… - American journal of …, 2016 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease involving pulmonary injury
associated with tissue repair, dysfunction and fibrosis. Recent studies indicate that some …

MicroRNA‑375 prevents TGF‑β‑dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathway

X Zhang, Q Chen, H Song, W Jiang… - Molecular …, 2020 - spandidos-publications.com
Transdifferentiation of lung fibroblasts to myofibroblasts is a crucial pathophysiological
process in pulmonary fibrosis. MicroRNA‑375 (miR‑375) was initially identified as a tumor …

Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

P Wei, Y Xie, PW Abel, Y Huang, Q Ma, L Li, J Hao… - Cell death & …, 2019 - nature.com
Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of
idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to …

The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis

C Liang, X Li, L Zhang, D Cui, X Quan… - … and Molecular Pathology, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial fibrotic lung disease with an
undefined etiology and no effective treatments. By binding to cell surface receptors …

miR-130b-3p modulates epithelial-mesenchymal crosstalk in lung fibrosis by targeting IGF-1

S Li, J Geng, X Xu, X Huang, D Leng, D Jiang, J Liang… - PloS one, 2016 - journals.plos.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and usually lethal fibrotic lung
disease with largely unknown etiology and pathogenesis. Evidence suggests microRNAs …

Integrated analyses identify the involvement of microRNA-26a in epithelial–mesenchymal transition during idiopathic pulmonary fibrosis

H Liang, Y Gu, T Li, Y Zhang, L Huangfu, M Hu… - Cell death & …, 2014 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and highly lethal
fibrotic lung disease with poor treatment and unknown etiology. Emerging evidence …

TGF-β1-induced miR-424 promotes pulmonary myofibroblast differentiation by targeting Slit2 protein expression

Y Huang, Y Xie, PW Abel, P Wei, J Plowman… - Biochemical …, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with irreversible
loss of lung tissue and function. Myofibroblasts in the lung are key cellular mediators of IPF …