White matter (WM) degeneration is suggested to predict the early signs of Alzheimer's
disease (AD). The exact structural regions of brain circuitry involved are not known. This …

Studies that examined white matter (WM) alterations in amnestic mild cognitive impairment
(aMCI) abound. This timely meta-analysis aims to synthesize the results of these studies …

Background Cognitive reserve is most commonly measured using socio-behavioural proxy
variables. These variables are easy to collect, have a straightforward interpretation, and are …

It has recently been reported that the evolutionarily ancestral alleles of two functional
polymorphisms in the β 2-adrenergic receptor gene (ADRB2) were related to higher …

Mild cognitive impairment (MCI) is a heterogeneous group and certain MCI subsets
eventually convert to dementia. Cerebrospinal fluid (CSF) biomarkers are known to predict …

Background: Normal aging is accompanied by a decline of cognitive abilities, and executive
skills may be affected selectively, but the underlying mechanisms remain obscure and …

Structural brain change and concomitant cognitive decline are the seemingly unavoidable
escorts of aging. Despite accumulating studies detailing the effects of age on the brain and …

We explored whether white matter (WM) integrity in cognitively normal (CN) older adults is
associated with cerebrospinal fluid (CSF) markers of Alzheimer's disease pathology. Twenty …

The purposes of this study were to explore the association between cognitive performance
and white matter lesions (WMLs), and to investigate whether it is possible to predict …

White matter (WM) integrity in the medial temporal lobes and episodic memory performance
were examined in patients with mild cognitive impairment (MCI) and age-matched …