Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma

M Yotsukura, H Yasuda, T Shigenobu, K Kaseda… - Lung Cancer, 2017 - Elsevier
Objectives Over the past decade, the biological and clinical characteristics of lung cancer
with epidermal growth factor receptor (EGFR) mutation have been well studied. However …

Clinical impacts of EGFR mutation status: analysis of 5780 surgically resected lung cancer cases

K Suda, T Mitsudomi, Y Shintani, J Okami, H Ito… - The Annals of thoracic …, 2021 - Elsevier
Background To elucidate the clinical, pathologic, and prognostic impacts of epidermal
growth factor receptor (EGFR) mutation and mutation subtypes in early-stage lung cancer …

Epidermal growth factor receptor mutation as a risk factor for recurrence in lung adenocarcinoma

K Hayasaka, S Shiono, Y Matsumura… - The Annals of Thoracic …, 2018 - Elsevier
Background The presence of epidermal growth factor receptor (EGFR) mutations is an
established prognostic factor for patients with advanced lung adenocarcinoma. Here, we …

[HTML][HTML] Prognostic impacts of EGFR mutation status and subtype in patients with surgically resected lung adenocarcinoma

K Takamochi, S Oh, T Matsunaga, K Suzuki - The Journal of thoracic and …, 2017 - Elsevier
Objective Epidermal growth factor receptor (EGFR) gene mutation status is a well-
established predictor of the efficacy of EGFR tyrosine-kinase inhibitor (TKI) therapy in …

Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma

T Nishii, T Yokose, Y Miyagi, Y Daigo… - Asia‐Pacific Journal …, 2017 - Wiley Online Library
Aim With the advent of the molecular‐targeted therapy, rapid progress has been made in the
treatment of advanced or recurrent non‐small‐cell lung cancer (NSCLC). Although surgical …

Prognostic impact of EGFR driver mutations on postoperative disease recurrence in lung adenocarcinoma

T Okamoto, H Kitahara, S Shimamatsu… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: The purpose of this study was to investigate the prognostic significance of epidermal
growth factor receptor (EGFR) sensitizing mutations in patients with lung adenocarcinoma …

EGFR mutations are more frequent in well-differentiated than in poor-differentiated lung adenocarcinomas

Y Liu, ML Xu, HH Zhong, WJ Heng, BQ Wu - Pathology & Oncology …, 2008 - Springer
Somatic mutations in epidermal growth factor receptor (EGFR) tyrosine kinase domain,
particularly deletions in exon 19 and point mutation in exon 21, are associated with clinical …

[HTML][HTML] Prognostic value of epidermal growth factor receptor gene mutation in resected lung adenocarcinoma

C Deng, Y Zhang, Z Ma, F Fu, L Deng, Y Li… - The Journal of thoracic …, 2021 - Elsevier
Background Mutation of the EGFR gene is known as a predictor for the response to EGFR
tyrosine kinase inhibitor. Although EGFR mutation status is proposed to be incorporated in …

Prognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma

H Zheng, Y Zhang, Y Zhan, S Liu, J Lu… - Cancer Management …, 2019 - Taylor & Francis
Purpose The purpose of this study was to investigate the relationship between epidermal
growth factor receptor (EGFR) gene mutation and clinicopathological features of lung …

Prognostic value of epidermal growth factor receptor mutations in resected lung adenocarcinomas

W Liu, L Zhao, Q Pang, Z Yuan, B Li, P Wang - Medical oncology, 2014 - Springer
The purpose of this study was to evaluate the association between epidermal growth factor
receptor (EGFR) mutations and prognosis in patients with completely resected lung …