Genome‐wide analysis of DNA methylation in endometriosis using Illumina Human Methylation 450 K BeadChips

L Wang, J Zhao, Y Li, Z Wang… - Molecular Reproduction …, 2019 - Wiley Online Library
Endometriosis is a common chronic gynecologic disorder characterized by the presence
and growth of endometrial‐like tissue outside of the uterine cavity. Although the exact …

[HTML][HTML] DNA methylation profiles of ovarian epithelial carcinoma tumors and cell lines

S Houshdaran, S Hawley, C Palmer, M Campan… - PloS one, 2010 - journals.plos.org
Background Epithelial ovarian carcinoma is a significant cause of cancer mortality in women
worldwide and in the United States. Epithelial ovarian cancer comprises several histological …

Comparison of genome-wide and gene-specific DNA methylation profiling in first-trimester chorionic villi from pregnancies conceived with infertility treatments

N Xu, GM Barlow, J Cui, ET Wang, B Lee… - Reproductive …, 2017 - journals.sagepub.com
Background: Assisted reproductive technologies are associated with altered methylation in
term placenta. However, it is unclear whether methylation patterns are the result of fertility …

[HTML][HTML] Ovarian cancer detection by DNA methylation in cervical scrapings

TI Wu, RL Huang, PH Su, SP Mao, CH Wu, HC Lai - Clinical Epigenetics, 2019 - Springer
Background Ovarian cancer (OC) is the most lethal gynecological cancer, worldwide, largely
due to its vague and nonspecific early stage symptoms, resulting in most tumors being found …

[HTML][HTML] Genome-wide assessment of DNA methylation in mouse oocytes reveals effects associated with in vitro growth, superovulation, and sexual maturity

MD Saenz-de-Juano, E Ivanova, K Billooye… - Clinical …, 2019 - Springer
Background In vitro follicle culture (IFC), as applied in the mouse system, allows the growth
and maturation of a large number of immature preantral follicles to become mature and …

[HTML][HTML] Integrated analysis of gene expression and DNA methylation profiles in ovarian cancer

G Gong, T Lin, Y Yuan - Journal of Ovarian Research, 2020 - Springer
Background Ovarian cancer is an epithelial malignancy that intrigues people for its poor
outcome and lack of efficient treatment, while methylation is an important mechanism that …

[HTML][HTML] Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer

DC Koestler, P Chalise, MS Cicek… - BMC medical …, 2014 - Springer
Background Both genetic and epigenetic factors influence the development and progression
of epithelial ovarian cancer (EOC). However, there is an incomplete understanding of the …

Hypomethylation of the LH/choriogonadotropin receptor promoter region is a potential mechanism underlying susceptibility to polycystic ovary syndrome

P Wang, H Zhao, T Li, W Zhang, K Wu, M Li… - …, 2014 - academic.oup.com
Our previous genome-wide association study identified LH/choriogonadotropin receptor
(LHCGR) as a susceptibility gene for polycystic ovary syndrome (PCOS). The objective of …

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells

F Qu, FF Wang, R Yin, GL Ding, M El-Prince… - Journal of molecular …, 2012 - Springer
The objective of this study was to explore whether hyperandrogenism induces epigenetic
alterations of peroxisome proliferator-activated receptor gamma 1 (PPARG1), nuclear …

Targeted genome-wide methylation and gene expression analyses reveal signaling pathways involved in ovarian dysfunction after developmental EDC exposure in …

AM Zama, M Uzumcu - Biology of reproduction, 2013 - academic.oup.com
Transient exposure to methoxychlor (MXC), an environmental endocrine-disrupting
chemical, during fetal and neonatal stages causes ovarian dysfunction in pubertal, adult …