Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice

N Khan, F Afaq, MH Kweon, KM Kim, H Mukhtar - Cancer research, 2007 - AACR
To develop novel mechanism-based preventive approaches for lung cancer, we examined
the effect of oral consumption of a human achievable dose of pomegranate fruit extract …

Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice

N Khan, N Hadi, F Afaq, DN Syed, MH Kweon… - …, 2007 - academic.oup.com
Developing novel mechanism-based chemopreventive approaches for lung cancer through
the use of dietary substances which humans can accept has become an important goal. In …

Cancer chemoprevention by pomegranate: laboratory and clinical evidence

VM Adhami, N Khan, H Mukhtar - Nutrition and cancer, 2009 - Taylor & Francis
Pomegranate fruit from the tree Punica granatum has been dubbed as the “nature's power
fruit.” Dating back to Biblical times, the tree itself is attributed to possess extraordinary …

Anthocyanin‐and hydrolyzable tannin‐rich pomegranate fruit extract modulates MAPK and NF‐κB pathways and inhibits skin tumorigenesis in CD‐1 mice

F Afaq, M Saleem, CG Krueger… - … journal of cancer, 2005 - Wiley Online Library
Chemoprevention has come of age as an effective cancer control modality; however, the
search for novel agent (s) for the armamentarium of cancer chemoprevention continues. We …

[HTML][HTML] Pomegranate for prevention and treatment of cancer: An update

P Sharma, SF McClees, F Afaq - Molecules, 2017 - mdpi.com
Cancer is the second leading cause of death in the United States, and those who survive
cancer may experience lasting difficulties, including treatment side effects, as well as …

Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer

A Malik, F Afaq, S Sarfaraz… - Proceedings of the …, 2005 - National Acad Sciences
Prostate cancer is the most common invasive malignancy and the second leading cause of
cancer-related deaths among US males, with a similar trend in many Western countries. One …

Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone–induced lung tumorigenesis model in A/J mice by tea …

G Lu, J Liao, G Yang, KR Reuhl, X Hao, CS Yang - Cancer research, 2006 - AACR
The present study investigated the inhibitory effects of Polyphenon E [a standardized green
tea polyphenol preparation containing 65%(−)-epigallocatechin-3-gallate] and caffeine on 4 …

Pomegranate derived products for cancer chemoprevention

DN Syed, F Afaq, H Mukhtar - Seminars in cancer biology, 2007 - Elsevier
Because treatment options for advanced metastasized cancers remain inadequate,
developing effective approaches for the prevention of cancer has become an important goal …

[HTML][HTML] Punica granatum (Pomegranate) activity in health promotion and cancer prevention

S Bassiri-Jahromi - Oncology reviews, 2018 - ncbi.nlm.nih.gov
Cancer has become one of the most fatal diseases in most countries. In spite of the medical
care developing, cancer still remains a significant problem. The majority of the cancers are …

Anticancer activities of pomegranate extracts and genistein in human breast cancer cells

MAL Jeune, J Kumi-Diaka, J Brown - Journal of medicinal food, 2005 - liebertpub.com
Previous studies have demonstrated the anticarcinogenic activity of pomegranate extracts
and genistein in a series of human cancer cells. In the present study, the potential anticancer …