Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin …
CJ Glueck, D Aregawi, M Agloria, Q Khalil… - Clinical …, 2006 - Elsevier
BACKGROUND:: Patients with high levels of low-density lipoprotein cholesterol (LDL-C)
might not tolerate 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (“statins”) …
might not tolerate 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (“statins”) …
Twelve-week, multicenter, randomized, open-label comparisonof the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: a DISCOVERY study
TE Strandberg, J Feely, EL Sigurdsson - Clinical therapeutics, 2004 - Elsevier
BACKGROUND:: Guidelines for the prevention of coronary heart disease (CHD) advocate
reductions in low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) levels as …
reductions in low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) levels as …
Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups
JW Blasetto, EA Stein, WV Brown, R Chitra… - The American journal of …, 2003 - Elsevier
A total of 5 randomized, double-blind trials in patients with hypercholesterolemia were
prospectively designed to allow pooling of plasma lipid data after 12 weeks of treatment. The …
prospectively designed to allow pooling of plasma lipid data after 12 weeks of treatment. The …
Efficacy and tolerability of once-weekly rosuvastatin in patients with previous statin intolerance
SP Kennedy, GP Barnas, MJ Schmidt… - Journal of Clinical …, 2011 - Elsevier
BACKGROUND: Many patients who could benefit from hydroxymethylglutaryl coenzyme-A
reductase inhibitors (statins) are unable to take statins because of myalgias while taking …
reductase inhibitors (statins) are unable to take statins because of myalgias while taking …
Rosuvastatin
CI Carswell, GL Plosker, B Jarvis - Drugs, 2002 - Springer
Abstract▴ Rosuvastatin is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …
inhibitor used in the treatment of patients with dyslipidaemia. Rosuvastatin is not extensively …
Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial)
PH Jones, MH Davidson, EA Stein, HE Bays… - The American journal of …, 2003 - Elsevier
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter
trial was to compare rosuvastatin with atorvastatin, pravastatin, and simvastatin across dose …
trial was to compare rosuvastatin with atorvastatin, pravastatin, and simvastatin across dose …
Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial
WV Brown, HE Bays, DR Hassman, J McKenney… - American heart …, 2002 - Elsevier
Objective The primary objective of this trial was to compare the efficacy of rosuvastatin with
that of pravastatin and simvastatin for lowering low-density lipoprotein cholesterol (LDL-C) …
that of pravastatin and simvastatin for lowering low-density lipoprotein cholesterol (LDL-C) …
Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial
JM McKenney, PH Jones, MA Adamczyk… - … medical research and …, 2003 - Taylor & Francis
SUMMARY In the Statin Therapies for Elevated Lipid Levels compared Across doses to
Rosuvastatin (STELLAR) trial, the efficacy of rosuvastatin calcium (Crestor) was compared …
Rosuvastatin (STELLAR) trial, the efficacy of rosuvastatin calcium (Crestor) was compared …
Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia
MH Davidson - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Rosuvastatin is a synthetic enantiomer that is hepatoselective, relatively hydrophilic and has
minimal metabolism via the cytochrome P450 3A4 system (similar to pravastatin) …
minimal metabolism via the cytochrome P450 3A4 system (similar to pravastatin) …
Review of efficacy of rosuvastatin 5 mg
T Teramoto, C Watkins - International journal of clinical practice, 2005 - Wiley Online Library
The prevalence of coronary heart disease (CHD) has been increasing in the past few
decades in Japan, as it has in industrialised countries worldwide. CHD risk can be …
decades in Japan, as it has in industrialised countries worldwide. CHD risk can be …