Meta-analysis identifies six new susceptibility loci for atrial fibrillation
PT Ellinor, KL Lunetta, CM Albert, NL Glazer… - Nature …, 2012 - nature.com
Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart
failure and death. We conducted a genome-wide association study (GWAS) in individuals of …
failure and death. We conducted a genome-wide association study (GWAS) in individuals of …
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death,. Fourteen genetic loci have been associated with atrial …
stroke, heart failure, and death,. Fourteen genetic loci have been associated with atrial …
[PDF][PDF] Genome-wide study of atrial fibrillation identifies seven risk loci and highlights biological pathways and regulatory elements involved in cardiac development
Atrial fibrillation (AF) is a common cardiac arrhythmia and a major risk factor for stroke, heart
failure, and premature death. The pathogenesis of AF remains poorly understood, which …
failure, and premature death. The pathogenesis of AF remains poorly understood, which …
Genome-wide association studies of atrial fibrillation: past, present, and future
Genome-wide association studies (GWAS) for atrial fibrillation (AF) have identified three
distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 that are associated with the …
distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 that are associated with the …
Multi-ethnic genome-wide association study for atrial fibrillation
Atrial fibrillation (AF) affects more than 33 million individuals worldwide and has a complex
heritability. We conducted the largest meta-analysis of genome-wide association studies …
heritability. We conducted the largest meta-analysis of genome-wide association studies …
Genetics of atrial fibrillation in 2020: GWAS, genome sequencing, polygenic risk, and beyond
Atrial fibrillation is a common heart rhythm disorder that leads to an increased risk for stroke
and heart failure. Atrial fibrillation is a complex disease with both environmental and genetic …
and heart failure. Atrial fibrillation is a complex disease with both environmental and genetic …
Common variation in atrial fibrillation: navigating the path from genetic association to mechanism
Atrial fibrillation (AF) is the most common cardiac arrhythmia with well-established clinical
and genetic risk components. Genome-wide association studies (GWAS) have identified 17 …
and genetic risk components. Genome-wide association studies (GWAS) have identified 17 …
Emerging directions in the genetics of atrial fibrillation
NR Tucker, PT Ellinor - Circulation research, 2014 - Am Heart Assoc
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased
morbidity. As the population ages and the prevalence of AF continues to rise, the …
morbidity. As the population ages and the prevalence of AF continues to rise, the …
Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation
Background—Atrial fibrillation (AF) affects> 30 million individuals worldwide and is
associated with an increased risk of stroke, heart failure, and death. AF is highly heritable …
associated with an increased risk of stroke, heart failure, and death. AF is highly heritable …
Genetics of atrial fibrillation: state of the art in 2017
Genetic variation is an important determinant of atrial fibrillation (AF) susceptibility.
Numerous rare variants in protein-coding sequences of genes have been associated with …
Numerous rare variants in protein-coding sequences of genes have been associated with …
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