Fabrication of porous hydroxyapatite scaffolds as artificial bone preform and its biocompatibility evaluation

DW Jang, RA Franco, SK Sarkar, BT Lee - Asaio Journal, 2014 - journals.lww.com
In this study, a novel porous hydroxyapatite scaffold was designed and fabricated to imitate
natural bone through a multipass extrusion process. The conceptual design manifested …

Bone tissue engineering with porous hydroxyapatite ceramics

H Yoshikawa, A Myoui - Journal of Artificial Organs, 2005 - Springer
The main principle of bone tissue engineering strategy is to use an osteoconductive porous
scaffold in combination with osteoinductive molecules or osteogenic cells. The requirements …

Characterization and osteoblast-like cell compatibility of porous scaffolds: bovine hydroxyapatite and novel hydroxyapatite artificial bone

Y Gao, WL Cao, XY Wang, YD Gong, JM Tian… - Journal of Materials …, 2006 - Springer
Three different porous scaffolds were tested. The first two were prepared by sintering bovine
bone. The third scaffold was prepared using three-dimensional gel-lamination, a new rapid …

A novel porous bioceramics scaffold by accumulating hydroxyapatite spherulites for large bone tissue engineering in vivo. II. Construct large volume of bone grafts

W Zhi, C Zhang, K Duan, X Li, S Qu… - … Research Part A, 2014 - Wiley Online Library
In vivo engineering of bone autografts using bioceramic scaffolds with appropriate porous
structures is a potential approach to prepare autologous bone grafts for the repair of critical …

Biological advantages of porous hydroxyapatite scaffold made by solid freeform fabrication for bone tissue regeneration

BJ Kwon, J Kim, YH Kim, MH Lee, HS Baek… - Artificial …, 2013 - Wiley Online Library
Presently, commercially available porous bone substitutes are manufactured by the
sacrificial template method, direct foaming method, and polymer replication method (PRM) …

Proliferation and mineralization of bone marrow cells cultured on macroporous hydroxyapatite scaffolds functionalized with collagen type I for bone tissue …

S Teixeira, MH Fernandes, MP Ferraz… - Journal of Biomedical …, 2010 - Wiley Online Library
This study concerns the preparation and in vitro characterization of functionalized
hydroxyapatite (HA) porous scaffolds, which are intended to be used as drug‐delivery …

Creating hierarchical porosity hydroxyapatite scaffolds with osteoinduction by three-dimensional printing and microwave sintering

X Pei, L Ma, B Zhang, J Sun, Y Sun, Y Fan, Z Gou… - …, 2017 - iopscience.iop.org
Hierarchical porosity, which includes micropores and macropores in scaffolds, contributes to
important multiple biological functions for tissue regeneration. This paper introduces a two …

Customized hybrid biomimetic hydroxyapatite scaffold for bone tissue regeneration

L Ciocca, IG Lesci, O Mezini, A Parrilli… - … Research Part B …, 2017 - Wiley Online Library
Abstract Three‐dimension (3D) scaffolds for bone tissue regeneration were produced
combining three different phases: nanometric hydroxyapatite (HA) was synthesized by …

Macroporous hydroxyapatite scaffolds for bone tissue engineering applications: Physicochemical characterization and assessment of rat bone marrow stromal cell …

JM Oliveira, SS Silva, PB Malafaya… - … Research Part A: An …, 2009 - Wiley Online Library
In this work, a new methodology is reported for developing hydroxyapatite (HA) scaffolds
using an organic sacrifice template. The novelty of work consists of possibility of obtaining …

3D hydroxyapatite scaffold for bone regeneration and local drug delivery applications

S Mondal, U Pal - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Bone tissue engineering is the technology of healing bone defects in critical clinical
conditions using functional tissue-engineering substitutes. Hydroxyapatite (HAp), as a …