In recent studies from Sweden and the United States, a high vitamin A intake has been
associated with low bone mineral density (BMD) and increased fracture risk. In Sweden and …

Excessive intake of vitamin A is postulated to have a detrimental effect on bone by inducing
osteoporosis. This may lead to an increased risk of fracture, particularly in persons who are …

Results: Median intake of vitamin A ranged from 684 retinol equivalents (REs)/day (quintile
1) to 2000 REs/day (quintile 5). After adjustment for confounders related to lifestyle and …

Background Excessive intakes of vitamin A have been shown to have adverse skeletal
effects in animals. High vitamin A intake may lead to an increased risk of fracture in humans …

ContextIngestion of toxic amounts of vitamin A affects bone remodeling and can have
adverse skeletal effects in animals. The possibility has been raised that long-term high …

BACKGROUND: Recent studies on the association between vitamin A and fracture risk have
focused on samples with high vitamin A intake. We analyzed a cohort that was more …

Limited data in humans and animals indicate that excess vitamin A stimulates bone
resorption and inhibits bone formation, effects that over time might lead to bone loss and …

VITAMIN A, an essential micronutrient, is provided by animal foods, whereas-carotene and
other carotenoids, known as provitamin A molecules, are derived from plant sources. In …

Background: Recent observational studies suggest that preformed vitamin A (VA) intakes of
1500–2000 μg/d may increase the risk of osteoporosis and hip fracture. However, few …

Results from observational studies of the association between vitamin A intake or serum
concentration and bone mineral density or fracture are mixed. The inconsistencies may be …