An extensible, scalable architecture for managing bioinformatics data and analyses

AR Shah, M Singhal, TD Gibson… - 2008 IEEE Fourth …, 2008 - ieeexplore.ieee.org
Systems biology research demands the availability of tools and technologies that span a
comprehensive range of computational capabilities, including data management, transfer …

Service-oriented laboratory information management system for life sciences research

SM Tharayil, T Kalbfleisch… - … Conference on Services …, 2007 - ieeexplore.ieee.org
Data and process management are among the biggest problems that the Life Sciences face
today, particularly in the areas of Genomics, Proteomics, and Metabolomics. This paper …

Optimized seamless integration of biomolecular data

BA Eckman, Z Lacroix, L Raschid - Proceedings 2nd Annual …, 2001 - ieeexplore.ieee.org
Today, scientific data is inevitably digitized, stored in a variety of heterogeneous formats,
and is accessible over the Internet. Scientists need to access an integrated view of multiple …

An interoperable data architecture for data exchange in a biomedical research network

D Crichton, H Kincaid, GJ Downing… - … IEEE Symposium on …, 2001 - ieeexplore.ieee.org
Knowledge discovery and data correlation require a unified approach to basic data
management. However, achieving such an approach is nearly impossible with hundreds of …

Software engineering challenges in bioinformatics

J Barker, J Thornton - Proceedings. 26th International …, 2004 - ieeexplore.ieee.org
Data from biological research is proliferating rapidly and advanced data storage and
analysis methods are required to manage it. We introduce the main sources of biological …

TAMBIS Online: a bioinformatics source integration tool

R Stevens, NW Paton, P Baker, G Ng… - … on Scientific and …, 1999 - ieeexplore.ieee.org
Conducting bioinformatic analyses involves biologists in expressing requests over a range
of heterogeneous information sources. The TAMBIS (Transparent Access to Multiple …

Exploring heterogeneous biological data sources

E Baralis, A Fiori - … workshop on database and expert systems …, 2008 - ieeexplore.ieee.org
Research activity in the life science area is becoming increasingly data intensive. Huge
amounts of highly heterogeneous data, including high throughput experiment results …

Building cyberinfrastructure for bioinformatics using service oriented architecture

WW Li, S Krishnan, K Mueller… - … Computing and the …, 2006 - ieeexplore.ieee.org
Cyberinfrastructure makes the development and deployment of bioinformatics applications
easier by providing the framework and components that may be loosely coupled using …

Integrating data-intensive computing systems with biological data analysis frameworks

E Pedersen, IA Raknes, M Ernstsen… - 2015 23rd Euromicro …, 2015 - ieeexplore.ieee.org
Biological data analysis is typically implemented using a pipeline that combines many data
analysis tools and meta-databases. These pipelines must scale to very large datasets, and …

Exploring architecture options for a federated, cloud-based system biology knowledgebase

I Gorton, Y Liu, J Yin - 2010 IEEE Second International …, 2010 - ieeexplore.ieee.org
Systems biology is characterized by a large community of scientists who use a wide variety
of fragmented and competing data sets and computational tools of all scales to support their …