The endoplasmic reticulum (ER) is an essential organelle involved in many cellular
functions including protein folding and secretion, lipid biosynthesis, and calcium …

The endoplasmic reticulum (ER) is a multifunctional organelle required for lipid biosynthesis,
calcium storage, and protein folding and processing. A number of physiological and …

In eukaryotic cells, the endoplasmic reticulum (ER) is an organelle that is responsible for
protein folding and assembly, lipid and sterol biosynthesis, and free calcium storage. In the …

The endoplasmic reticulum (ER) is a well-orchestrated protein-folding machine composed of
protein chaperones, proteins that catalyze protein folding, and sensors that detect the …

Endoplasmic reticulum (ER) is a dynamic organelle orchestrating the folding and post-
translational maturation of almost all membrane proteins and most secreted proteins. These …

The endoplasmic reticulum (ER)-induced unfolded protein response (UPR) is an adaptive
mechanism that is activated upon accumulation of misfolded proteins in the ER and aims at …

Cellular stress induced by the abnormal accumulation of unfolded or misfolded proteins at
the endoplasmic reticulum (ER) is emerging as a possible driver of human diseases …

The endoplasmic reticulum is an organelle with multiple functions. The synthesis of
transmembrane proteins and proteins that are to be secreted occurs in this organelle. Many …

Cellular mechanisms governing redox homeostasis likely involve their integration with other
stresses. Endoplasmic reticulum (ER) stress triggers complex adaptive or proapoptotic …

The endoplasmic reticulum (ER) is the cell organelle where secretory and membrane
proteins are synthesized and folded. Correctly folded proteins exit the ER and are …