Lipoprotein (a): a genetic risk factor for premature coronary heart disease

AM Scanu - JAMA, 1992 - jamanetwork.com
Lipoprotein (a)(Lp [a]) can be defined as a lipoprotein particle having as a protein moiety
apolipoprotein B-100 (the protein associated with low-density lipoprotein) disulfide-linked to …

Lipoprotein (a) in health and disease

F Kronenberg, A Steinmetz, GM Kostner… - Critical reviews in …, 1996 - Taylor & Francis
Abstract Lipoprotein (a)[Lp (a)] represents an LDL-like particle to which the Lp (a)-specific
apolipoprotein (a) is linked via a disulfide bridge. It has gained considerable interest as a …

Lipoprotein (a) as a risk factor for coronary artery disease

SM Marcovina, ML Koschinsky - The American journal of cardiology, 1998 - Elsevier
Since its identification by Kåre Berg in 1963, lipoprotein (a)[Lp (a)] has become a focus of
research interest owing to the results of case-control and prospective studies linking …

[HTML][HTML] Lipoprotein (a): biology and clinical importance

SPA McCormick - The Clinical Biochemist Reviews, 2004 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)[Lp (a)] is a unique lipoprotein that has emerged as an independent
risk factor for developing vascular disease. Plasma Lp (a) levels above the common cut-off …

Lipoprotein (a) an elusive cardiovascular risk factor

L Berglund, R Ramakrishnan - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Lipoprotein (a)[Lp (a)], is present only in humans, Old World nonhuman primates, and the
European hedgehog. Lp (a) has many properties in common with low-density lipoprotein …

Lipoprotein (a) and atherosclerosis: new perspectives on the mechanism of action of an enigmatic lipoprotein

ML Koschinsky - Current atherosclerosis reports, 2005 - Springer
Although elevated plasma concentrations of lipoprotein (a)(Lp (a)) have been identified as a
risk factor for coronary heart disease, the pathophysiologic and physiologic roles of Lp (a) …

Lipoprotein (a): A missing culprit in the management of athero‐thrombosis?

G Ferretti, T Bacchetti, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Lipoprotein (a) Lp (a) is a cholesterol‐rich, LDL‐like particle that is independently
associated with an increased risk for ischemic heart disease, atherosclerosis, thrombosis …

Atherothrombogenicity of lipoprotein (a): the debate

AM Scanu - The American journal of cardiology, 1998 - Elsevier
Although lipoprotein (a)(Lp [a]) has been recognized as an atherothrombogenic factor, the
underlying mechanisms for this pathogenicity have not been clearly defined. Plasma levels …

Genetic linkage between lipoprotein (a) phenotype and a DNA polymorphism in the plasminogen gene

DT Drayna, RA Hegele, PE Hass, M Emi, LL Wu… - Genomics, 1988 - Elsevier
Coronary heart disease risk correlates directly with plasma concentrations of lipoprotein
(a)(Lp (a)), a lowdensity lipoprotein-like particle distinguished by the presence of the …

Lipoprotein (a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart …

G Reyes-Soffer, HN Ginsberg, L Berglund… - … , and vascular biology, 2022 - Am Heart Assoc
High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …