The intricate physiology of many Central Nervous System (CNS) disorders points towards
oxidative damages of neurons. Various studies have established that oxidative stress is a …

It is proven that oxidative stress has a pivotal role in the process of neurodegeneration. The
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …

The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

Background: Neurodegeneration is a condition in which progressive loss of function and
structure of neurons occurs. Several lines of evidence suggest that oxidative stress has a …

Free radicals are common outcome of normal aerobic cellular metabolism. In-built
antioxidant system of body plays its decisive role in prevention of any loss due to free …

Oxidative stress has been consistently linked to ageing-related neurodegenerative
diseases. Neurodegenerative diseases are characterized by progressive dysfunction and …

A lot of evidence exists that oxidative stress is the primary cause of neurodegeneration.
Neurons are more susceptible to oxidative damage than other cells due to their high oxygen …

The distinguishing pathogenic features of neurodegenerative diseases include
mitochondrial dysfunction and derived reactive oxygen species generation. The neural …

Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

The neurodegenerative process is characterized by the progressive ultrastructural
alterations of selected classes of neurons accompanied by imbalanced cellular …