Oxidative stress (OS) has been implicated in the pathophysiology of many neurological,
particularly neurodegenerative diseases. OS can cause cellular damage and subsequent …

Alzheimer's disease (AD) is the leading cause of dementia, affecting millions of people
worldwide. Oxidative stress contributes towards induction of neurodegeneration. It is one of …

Oxidative insults, whether over-excitation, excessive release of glutamate or ATP caused by
stroke, ischemia or inflammation, exposure to ionizing radiation, heavy-metal ions or …

Objectives: Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen
(RNS) species, along with the failure of balancing effects of endogenous antioxidant …

The human body is highly complex and comprises a variety of living cells and extracellular
material, which forms tissues, organs, and organ systems. Human cells tend to turn over …

Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …

Free-radicals (Oxygen and Nitrogen species) are formed in mitochondria during the
oxidative phosphorylation. Their high reactivity, due to not-engaged electrons, leads to an …

Parkinson's disease and Alzheimer's disease are major progressive neurologic disorders,
the risk of which increases with advancing age (65 years and over). In familial cases …

The incidence and prevalence of neurodegenerative diseases (ND) increase with life
expectancy. This paper reviews the role of oxidative stress (OS) in ND and pharmacological …

Cellular antioxidants are known to change their redox state, and they can be targeted for
destruction, regulate oxidative processes involved in signal transduction, effect gene …