Recent advancements and growing attention about free radicals (ROS) and redox signaling
enable the scientific fraternity to consider their involvement in the pathophysiology of …

Introduction: Aging is a normal, inevitable, irreversible and progressive process which is
driven by internal and external factors. Oxidative stress, that is the imbalance between …

Various neurodegenerative disorders and syndromes are associated with oxidative stress.
The deleterious consequences of excessive oxidations and the pathophysiological role of …

Both physiological and pathological aging processes induce brain alterations especially
affecting the speed of processing, working memory, conceptual reasoning and executive …

Biochemical integrity of the brain is vital for normal functioning of the central nervous system
(CNS). One of the factors contributing to cerebral biochemical impairment is a chemical …

Oxidative stress plays a crucial role in Alzheimer's disease (AD) from its prodromal stage of
mild cognitive impairment. There is an interplay between oxidative stress and the amyloid β …

Reactive oxygen species and oxidative state are slowly gaining acceptance in having a
physiological relevance rather than just being the culprits in pathophysiological processes …

To counteract oxidative stress and associated brain diseases, antioxidant systems rescue
neuronal cells from oxidative stress by neutralizing reactive oxygen species and preserving …

Objectives The central nervous system (CNS) is essential for homeostasis and controls the
physiological functions of the body. However, the biochemical characteristics of the CNS …

Systemic oxidative stress (SOS) has an important role in the mechanisms activation of
neuronal death, involved in the neurodegenerative disease (ND) etiology. Brain is …