Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity

V Calabrese, C Cornelius, C Mancuso, G Pennisi… - Neurochemical …, 2008 - Springer
The predominant molecular symptom of aging is the accumulation of altered gene products.
Moreover, several conditions including protein, lipid or glucose oxidation disrupt redox …

[HTML][HTML] The specificity of neuroprotection by antioxidants

Y Liu, DR Schubert - Journal of biomedical science, 2009 - Springer
Background Reactive oxygen species (ROS) play an important role in aging and age-related
diseases such as Parkinson's disease and Alzheimer's disease. Much of the ROS …

[HTML][HTML] Biomechanistic insights into the roles of oxidative stress in generating complex neurological disorders

M Yusuf, M Khan, MA Robaian, RA Khan - Biological chemistry, 2018 - degruyter.com
Neurological diseases like Alzheimer's disease, epilepsy, parkinsonism, depression,
Huntington's disease and amyotrophic lateral sclerosis prevailing globally are considered to …

Vitamin E and other antioxidants in neuroprotection

Behl - International journal for vitamin and nutrition research, 1999 - econtent.hogrefe.com
Several pathological conditions are believed to be causally related to the generation of
reactive oxygen species and free radicals including various neurodegenerative disorders. In …

Oxygen free radicals and brain dysfunction

JA Jesberger, JS Richardson - International journal of …, 1991 - Taylor & Francis
Oxygen free radicals, any chemical moiety containing an oxygen atom with an unpaired
electron in the outer orbital shell, are generated during many normal biochemical reactions …

[HTML][HTML] Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

Pathogenesis of neurodegenerative diseases and the protective role of natural bioactive components

S Samanta, S Chakraborty, D Bagchi - Journal of the American …, 2024 - Taylor & Francis
Neurodegenerative diseases are a serious problem throughout the world. There are several
causes of neurodegenerative diseases; these include genetic predisposition, accumulation …

[HTML][HTML] Oxidative stress in neurodegenerative diseases

E Niedzielska, I Smaga, M Gawlik, A Moniczewski… - Molecular …, 2016 - Springer
The pathophysiologies of neurodegenerative diseases, including amyotrophic lateral
sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD), are far from being …

Research progress of antioxidants in oxidative stress therapy after spinal cord injury

C Zhang, T Zhai, J Zhu, D Wei, S Ren, Y Yang… - Neurochemical …, 2023 - Springer
Spinal cord injury (SCI) is a serious problem in the central nervous system resulting in high
disability and mortality with complex pathophysiological mechanisms. Oxidative stress is …

Natural bioactive molecules as neuromedicines for the treatment/prevention of neurodegenerative diseases

A Babazadeh, FM Vahed, Q Liu, SA Siddiqui… - ACS …, 2023 - ACS Publications
The brain is vulnerable to different types of stresses, particularly oxidative stress as a result
of oxygen requirements/utilization in the body. Large amounts of unsaturated fatty acids …