Hydroxyapatite (HAP) is the major biomineral of bone. Despite the large number of studies
addressing HAP formation, a fundamental understanding of the critical roles of HAP-forming …

Biomineralization templated by non-collagenous proteins is an example how nature uses
nanotechnology to strengthen the load-bearing skeletons of vertebrates.[1–3] Mineralized …

矿化胶原纤维是天然骨的主要成分, 掌握胶原纤维的生物矿化过程, 原理和调控机制对于骨修复
材料的设计及骨组织的再生修复发展有重要意义. 综述了体外模拟胶原纤维矿化的研究进展 …

Biological mineralization relies upon proteins which preferentially nucleate minerals and
control their growth. This process is often referred to as “templating”, but the term is inclusive …

Bone is the sole biological material found in the human body that is able to sustain
compressive loads. However, although the structure of bone is well-known (it is a natural …

The adaptive response of bones to mechanical loading is essential for musculoskeletal
development. Despite the importance of collagen in bone mineralization, little is known …

Due to an increasing demand for more functional bone-repair materials, implants composed
of mineralized collagen have garnered interest. The process as to how collagen fibrils …

Biomineralized collagen composite materials pose an intriguing alternative to current
synthetic bone graft substitutes by offering a biomimetic composition that closely resembles …

The complex morphologies of mineralised collagen fibrils are regulated through interactions
between the collagen matrix and non-collagenous extracellular proteins. In the present …