Breast cancer is a global health concern, with increasing disease burden and disparities in
access to healthcare. Late diagnosis and limited treatment options in underserved areas …

Abstract Lead molecules containing 1, 4‐quinone moiety are intriguing novel compounds
that can be utilized to treat cancer owing to their antiproliferative activities. Nine previously …

Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …

In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …

Recently, quinoline has become an essential heterocyclic compound due to its versatile
applications in the fields of industrial and synthetic organic chemistry. It is a vital scaffold for …

Introduction: Quinazoline and quinazolinone scaffolds represent an important class of
biologically active nitrogen heterocyclic compounds. A variety of marketed drugs are based …

Objective: Conjugating quinolones with different bioactive pharmacophores to obtain potent
anticancer active agents. Methods: Fused pyrazolopyrimidoquinolines 3a-d, Schiff bases 5 …

4‐Quinolone derivatives are serving as active components in diverse families of drugs such
as antibacterial, antiviral, antimalarial, anticancer, antitumor and anti‐HIV agents. They have …

Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Drug resistance is the major cause of the failure of cancer chemotherapy, so one of the most
important features in developing effective cancer therapeutic strategies is to overcome drug …