Dry powder inhaler formulation

MJ Telko, AJ Hickey - Respiratory care, 2005 - rc.rcjournal.com
A drug product combines pharmacologic activity with pharmaceutical properties. Desirable
performance characteristics are physical and chemical stability, ease of processing …

Dry powder aerosol drug delivery—Opportunities for colloid and surface scientists

HK Chan - Colloids and Surfaces A: Physicochemical and …, 2006 - Elsevier
Development of dry powder aerosol drug delivery system includes powder production,
formulation, dispersion, and delivery of the powder aerosol to the lung. Conventional …

The nanoscale in pulmonary delivery. Part 2: formulation platforms

PGA Rogueda, D Traini - Expert opinion on drug delivery, 2007 - Taylor & Francis
This article is the second part of a review on the nanoscale in pulmonary drug delivery.
Specifically it summarises and analyses the potential of the different inhalation delivery …

[HTML][HTML] Particle engineering in dry powders for inhalation

R Scherließ, S Bock, N Bungert, A Neustock… - European Journal of …, 2022 - Elsevier
Drug administration by inhalation is a well-established approach to treat respiratory and
systemic diseases. To deliver a drug into the lung dry powder inhalation (DPI) is an …

Recent advances in aerosolised drug delivery

A Chandel, AK Goyal, G Ghosh, G Rath - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Pulmonary route is extensively studied for the diagnosis and treatment of pulmonary and
extra pulmonary disease conditions such as asthma, tuberculosis, emphysema, and …

Formulation techniques for high dose dry powders

AD Brunaugh, HDC Smyth - International journal of pharmaceutics, 2018 - Elsevier
Delivery of drugs to the lungs via dry powder inhaler (DPI) is a promising approach for the
treatment of both local pulmonary conditions and systemic diseases. Though DPIs are …

Emerging inhalation aerosol devices and strategies: where are we headed?

QT Zhou, P Tang, SSY Leung, JGY Chan… - Advanced drug delivery …, 2014 - Elsevier
Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …

[HTML][HTML] Natural and bioinspired excipients for dry powder inhalation formulations

D Zillen, M Beugeling, WLJ Hinrichs, HW Frijlink… - Current Opinion in …, 2021 - Elsevier
Pulmonary drug delivery can have several advantages over other administration routes, in
particular when using dry powder formulations. Such dry powder inhalation formulations …

Critical parameters for particle-based pulmonary delivery of chemotherapeutics

A Dabbagh, NH Abu Kasim, CH Yeong… - Journal of aerosol …, 2018 - liebertpub.com
Targeted delivery of chemotherapeutics through the respiratory system is a potential
approach to improve drug accumulation in the lung tumor, while decreasing their negative …

Dry powder inhalers in COPD, lung inflammation and pulmonary infections

P Muralidharan, D Hayes Jr… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: The number of pulmonary diseases that are effectively treated by aerosolized
medicine continues to grow. Areas covered: These diseases include chronic obstructive …