Inhalation therapy is one of the oldest approaches to the therapy of diseases of the
respiratory tract. It is well recognised today that the most effective and safe means of treating …

Drugs for inhalation are no longer exclusively highly crystalline small molecules. They may
also be amorphous small molecules, peptides, antibodies, and myriad types of engineered …

Aerosols are dynamic systems, responding to variations in the surrounding environmental
conditions by changing in size, composition and phase. Although, widely used in inhalation …

Development of dry powder inhalers involves powder recrystallization, formulation,
dispersion, delivery, and deposition of the therapeutic agent in different regions of the …

Research in the area of pulmonary drug delivery has gathered momentum in the last several
years, with increased interest in using the lung as a means of delivering drugs systemically …

In comparison with pressurized metered dose inhalers (pMDIs), dry powder inhalers (DPIs)
emit a semistable aerosol cloud and are inspiratory flow actuated and inspiratory flow …

Abstract Purpose. Relatively large (> 5 µm) and porous (mass density< 0.4 g/cm 3) particles
present advantages for the delivery of drugs to the lungs, eg, excellent aerosolization …

Although the Spinhaler has been available for many years as a delivery device for sodium
cromoglycate powder, the quantity of powder delivered to the lungs and the optimal mode of …

In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

Drug delivery to the lungs is an effective way of targeting inhaled therapeutic aerosols and
treating obstructive airway diseases, such as asthma and chronic obstructive pulmonary …