Delivery technologies for orally inhaled products: an update

C Moon, HDC Smyth, AB Watts, RO Williams III - AAPS PharmSciTech, 2019 - Springer
Orally inhaled products have well-known benefits. They allow for effective local
administration of many drugs for the treatment of pulmonary disease, and they allow for …

Overcoming the pulmonary barrier: New insights to improve the efficiency of inhaled therapeutics

X Murgia, C de Souza Carvalho… - European Journal of …, 2014 - degruyter.com
The pulmonary route offers an exceptional, non-invasive administration site for drug
delivery. The principal characteristics that make the lungs an appealing route for drug …

Dispersion and characterization of pharmaceutical dry powder aerosols

CA Dunber, AJ Hickey, P Holzner - KONA Powder and Particle …, 1998 - jstage.jst.go.jp
Dry powder inhalers may be employed for the delivery of drugs to the lungs for the treatment
of pulmonary and systemic diseases. Dry powder inhalers consist of a formulation, metering …

Dry powder inhalers for optimal drug delivery

SP Newman - Expert opinion on biological therapy, 2004 - Taylor & Francis
Dry powder inhalers (DPIs) have been available for delivering drugs to the lungs for over 30
years. In the last decade there has been a big increase in DPI development, resulting partly …

Targeted delivery of inhaled drugs: current challenges and future goals

D GANDERTON - Journal of aerosol medicine, 1999 - liebertpub.com
Past success of topical delivery to the lung stems more from the therapeutic nature of drugs
used rather than the delivery device. Both the pressurized metered dose inhaler (pMDI) and …

[图书][B] Controlled pulmonary drug delivery

HDC Smyth, AJ Hickey - 2011 - books.google.com
The pace of new research and level of innovation repeatedly introduced into the field of drug
delivery to the lung is surprising given its state of maturity since the introduction of the …

Particle engineering for pulmonary drug delivery

AHL Chow, HHY Tong, P Chattopadhyay… - Pharmaceutical …, 2007 - Springer
With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

Delivery of biotherapeutics by inhalation aerosol

RW Niven - Critical Reviews™ in Therapeutic Drug Carrier …, 1995 - dl.begellhouse.com
The role of inhalation therapy is adapting to changes brought on by advances in several
related disciplines. These range from device technology to the molecular and cell biology of …

Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance

C Bosquillon, C Lombry, V Preat, R Vanbever - Journal of controlled release, 2001 - Elsevier
The objective of this study was to determine the effects of formulation excipients and
physical characteristics of inhalation particles on their in vitro aerosolization performance …

Pharmaceutical dry powder aerosols: correlation of powder properties with dose delivery and implications for pharmacodynamic effect

NM Concessio, MM VanOort, MR Knowles… - Pharmaceutical …, 1999 - Springer
Purpose. Efficient dispersion of bulk solids is critical for dry powder aerosol production which
can be viewed as a sequence of events from stationary through dilated, flowing and finally …