Receptors and Channels Associated with Alcohol Use: Contributions from Drosophila
KM Scaplen, E Petruccelli - Neuroscience Insights, 2021 - journals.sagepub.com
Alcohol Use Disorder (AUD) is a debilitating disorder that manifests as problematic patterns
of alcohol use. At the core of AUD's behavioral manifestations are the profound structural …
of alcohol use. At the core of AUD's behavioral manifestations are the profound structural …
Insights from intoxicated Drosophila
E Petruccelli, KR Kaun - Alcohol, 2019 - Elsevier
Our understanding of alcohol use disorder (AUD), particularly alcohol's effects on the
nervous system, has unquestionably benefited from the use of model systems such as …
nervous system, has unquestionably benefited from the use of model systems such as …
The Neurotransmitters Involved in Drosophila Alcohol-Induced Behaviors
MM Chvilicek, I Titos, A Rothenfluh - Frontiers in behavioral …, 2020 - frontiersin.org
Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …
The genetics of alcohol responses of invertebrate model systems
A Rothenfluh, BR Troutwine… - Neurobiology of …, 2014 - utsouthwestern.elsevierpure.com
Alcohol use disorders and alcoholism are prevalent conditions that come at a high cost for
individuals and for society at large. About half the factors contributing to the development of …
individuals and for society at large. About half the factors contributing to the development of …
Unraveling the mechanisms of behaviors associated with AUDs using flies and worms
H Scholz - Alcoholism: Clinical and Experimental Research, 2019 - Wiley Online Library
Alcohol use disorders (AUDs) are very common worldwide and negatively affect both
individuals and societies. To understand how normal behavior turns into uncontrollable use …
individuals and societies. To understand how normal behavior turns into uncontrollable use …
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder
M Grotewiel, JC Bettinger - Alcoholism: Clinical and …, 2015 - Wiley Online Library
Background Despite the profound clinical significance and strong heritability of alcohol use
disorder (AUD), we do not yet have a comprehensive understanding of the naturally …
disorder (AUD), we do not yet have a comprehensive understanding of the naturally …
Synaptic Mechanisms of Ethanol Tolerance and Neuroplasticity: Insights from Invertebrate Models
A Bhandari, A Seguin, A Rothenfluh - International Journal of Molecular …, 2024 - mdpi.com
Alcohol tolerance is a neuroadaptive response that leads to a reduction in the effects of
alcohol caused by previous exposure. Tolerance plays a critical role in the development of …
alcohol caused by previous exposure. Tolerance plays a critical role in the development of …
Studying alcohol use disorder using Drosophila melanogaster in the era of 'Big Data'
Our understanding of the networks of genes and protein functions involved in Alcohol Use
Disorder (AUD) remains incomplete, as do the mechanisms by which these networks lead to …
Disorder (AUD) remains incomplete, as do the mechanisms by which these networks lead to …
Addiction-like behavior in Drosophila
AV Devineni, U Heberlein - Communicative & integrative biology, 2010 - Taylor & Francis
Alcohol abuse is a pervasive problem known to be influenced by genetic factors, yet our
understanding of the mechanisms underlying alcohol addiction is far from complete …
understanding of the mechanisms underlying alcohol addiction is far from complete …
Long-lasting, experience-dependent alcohol preference in Drosophila
SA Ojelade, PS Penninti, RJ Dove, MJ Nye… - Addiction …, 2013 - pmc.ncbi.nlm.nih.gov
To understand the molecular and neural mechanisms underlying alcohol addiction, many
models ranging from vertebrates to invertebrates have been developed. In Drosophila …
models ranging from vertebrates to invertebrates have been developed. In Drosophila …