Sterile inflammation occurs in acute conditions, such as ischemia reperfusion injury and
crystal-induced arthritis, as well as with chronic diseases, such as particle-induced lung …

It is evident that components of the extracellular matrix (ECM) act as danger-associated
molecular patterns (DAMPs) through direct interactions with pattern recognition receptors …

It is well known that necrotic cells are capable of promoting inflammation through releasing
so‐called endogenous 'danger signals' that can promote activation of macrophages …

Neutrophils are recruited to a site of infection or injury where they help initiate the acute
inflammatory response. In instances of sterile inflammation, where no microbial threats are …

There is increasing interest by physicians in the impact of the innate immune system on
human diseases. In particular, the role of the molecules that initiate and amplify innate …

In reply to internal or external danger stimuli, the body orchestrates an inflammatory
response. The endogenous triggers of this process are the damage-associated molecular …

Immune responses are initiated and perpetuated by molecules derived from microorganisms
pathogen-associated molecular-pattern molecules or from the damage or death of host cells …

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules
produced in cellular damage or stress, and they can activate the innate immune system …

Significance: Damage-associated molecular patterns (DAMPs) and pathogen-associated
molecular patterns (PAMPs) emanate from burn-injured tissue and enter systemic …

When cells die in vivo, they trigger an inflammatory response. The ensuing hyperemia, leak
of plasma proteins, and recruitment of leukocytes serve a number of useful functions in host …